Kariya Shin, Okano Mitsuhiro, Nishizaki Kazunori
Shin Kariya, Mitsuhiro Okano, Kazunori Nishizaki, Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
World J Gastroenterol. 2014 Feb 14;20(6):1470-84. doi: 10.3748/wjg.v20.i6.1470.
Helicobacter pylori (H. pylori) is a major cause of chronic gastritis and gastric ulcers and considerable evidence supports the notion that infection with this bacterium is also associated with gastric malignancy in addition to various other conditions including pulmonary, vascular and autoimmune disorders. Gastric juice infected with H. pylori might play an important role in upper respiratory tract infection. Although direct and/or indirect mechanisms might be involved in the association between H. pylori and upper respiratory tract diseases, the etiological role of H. pylori in upper respiratory tract disorders has not yet been fully elucidated. Although various studies over the past two decades have suggested a relationship between H. pylori and upper respiratory tract diseases, the findings are inconsistent. The present overview describes the outcomes of recent investigations into the impact of H. pylori on upper respiratory tract and adjacent lesions.
幽门螺杆菌（H. pylori）是慢性胃炎和胃溃疡的主要病因，大量证据支持这样一种观点，即除了包括肺部、血管和自身免疫性疾病在内的各种其他病症外，感染这种细菌还与胃部恶性肿瘤有关。感染幽门螺杆菌的胃液可能在上呼吸道感染中起重要作用。尽管幽门螺杆菌与上呼吸道疾病之间的关联可能涉及直接和/或间接机制，但幽门螺杆菌在上呼吸道疾病中的病因学作用尚未完全阐明。尽管在过去二十年中，各种研究表明幽门螺杆菌与上呼吸道疾病之间存在关联，但研究结果并不一致。本综述描述了最近关于幽门螺杆菌对上呼吸道及相邻病变影响的调查结果。
