Joshi M V, Patil D R, Tupe C D, Umarani U B, Ayachit V M, Geevarghese G, Mishra A C
National Institute of Virology, Pune 411 001, Maharashtra, India.
Acta Virol. 2005;49(1):69-71.
In order to determine the possible role of domestic animals in the outbreak of acute encephalitis associated with Chandipura virus (CPV) among children in Andhra Pradesh in 2003, a serological survey of domestic animals was carried out during the epidemic in July 2003. Out of 180 animal sera from highly affected areas of the Karimnagar and Warangal districts of Andhra Pradesh 33 (18.3%) had virus neutralizing (VN) antibodies to CPV. The positive animals consisted of pigs (30.6%), buffalos (17.9%), cattle (14.3%), goats (9.3%) and sheep (7.7%). Isolation of CPV and detection of CPV antibodies in patients with encephalitis reported earlier and the evidence of antibodies to CPV in domestic animals shown here suggest that CPV circulates in this region and should be considered an emerging virus of public health importance.
为确定家畜在2003年安得拉邦儿童中与钱迪普拉病毒（CPV）相关的急性脑炎暴发中可能起到的作用，于2003年7月疫情期间对家畜进行了血清学调查。在安得拉邦卡里姆纳加尔和瓦朗加尔地区受影响严重区域采集的180份动物血清中，33份（18.3%）具有针对CPV的病毒中和（VN）抗体。阳性动物包括猪（30.6%）、水牛（17.9%）、牛（14.3%）、山羊（9.3%）和绵羊（7.7%）。此前报告的脑炎患者中CPV的分离及CPV抗体检测，以及此处显示的家畜中CPV抗体证据表明，CPV在该地区传播，应被视为一种具有公共卫生重要性的新兴病毒。
