Campbell Robert M
Sibley Heart Center/Children's Health Care of Atlanta, GA 30329, USA.
Semin Pediatr Neurol. 2005 Mar;12(1):59-66. doi: 10.1016/j.spen.2005.01.002.
The treatment for pediatric causes for sudden cardiac death can either be general and supportive or, in 2005, can be much more etiology specific. While antiarrhythmic therapy and activity restriction have been for years the mainstay of therapy, newer technologies such as radiofrequency ablation and automatic implantable cardioverter defibrillators (AICDs) are now more commonly applied for certain disease entities. The evolving role for clinical genetic testing to determine the specific etiology of pediatric sudden cardiac death continues to evolve. Further improvements in risk stratification will allow us to determine which patients are at greatest risk, so that aggressive treatment can be delivered to these subgroups. In the future, there may be gene-specific therapies and/or genetic modification.
小儿心源性猝死的治疗方法既可以是一般性的支持治疗，也可以在2005年针对特定病因进行更具针对性的治疗。多年来，抗心律失常治疗和活动限制一直是主要的治疗手段，而诸如射频消融和自动植入式心脏复律除颤器（AICD）等新技术现在更常用于某些疾病实体。临床基因检测在确定小儿心源性猝死特定病因方面不断演变的作用仍在继续发展。风险分层的进一步改进将使我们能够确定哪些患者风险最高，从而对这些亚组患者进行积极治疗。未来，可能会有基因特异性疗法和/或基因改造。
