Soni Anand, LeLorier Paul
Section of Cardiology, C-8, Boston Medical Center, 88 East Newton Street, Boston, MA 02118, USA.
Curr Heart Fail Rep. 2005 Sep;2(3):118-23. doi: 10.1007/s11897-005-0019-x.
Sudden cardiac death is a frequent cause of death and has been well studied in the setting of both ischemic and dilated cardiomyopathies. The primary and secondary prevention of sudden cardiac death has not been the focus of randomized clinical trials in the large cohort of patients with nondilated, nonischemic cardiomyopathies, however. Those disorders include hypertrophic cardiomyopathy and its apical variant, arrhythmogenic right ventricular cardiomyopathy, takotsubo cardiomyopathy, left ventricular noncompaction, cardiac amyloidosis, and cardiac sarcoidosis. In these conditions, risk stratification for sudden death is based on observational data.
心源性猝死是常见的死亡原因，在缺血性和扩张型心肌病的背景下已得到充分研究。然而，在大量非扩张型、非缺血性心肌病患者中，心源性猝死的一级和二级预防并非随机临床试验的重点。这些疾病包括肥厚型心肌病及其心尖变异型、致心律失常性右心室心肌病、应激性心肌病、左心室心肌致密化不全、心脏淀粉样变性和心脏结节病。在这些情况下，猝死的风险分层基于观察数据。
