Reeves J W, Meeson S, Birch M J
Department of Clinical Physics, Royal London Hospital, 56-76 Ashfield Street, London, E1 1BB, UK.
Phys Med Biol. 2005 Jun 21;50(12):2955-65. doi: 10.1088/0031-9155/50/12/015. Epub 2005 Jun 1.
Barrett's oesophagus is considered to increase the risk of cancer 30 fold. A set of helical microwave antennas was designed to investigate their potential use in the thermal therapy of Barrett's oesophagus. For treatment, a balloon filled with muscle-equivalent material encapsulates the antenna. The effects of insertion depth and coil-spacing on the thermal distribution produced by the antennas (20-35 mm) were characterized. The 35 mm helical antenna, with a coil-spacing of 3.6 mm resulted in uniform heating for an insertion depth of 40 mm. It was observed that the resultant temperature distribution produced, by the antennas, was dependent on the insertion depth within the phantom. For all antennas studied, deeper insertion resulted in two high intensity regions, approximately 1/4 and 3/4 along the antenna length. In contrast, shallow insertion resulted in predominant tip heating with undesirable heating at the phantom entry point. However, by manipulating the coil-spacing of the helix, uniform temperature profiles were achieved for a range of insertion depths.
巴雷特食管被认为会使患癌风险增加30倍。设计了一组螺旋微波天线，以研究其在巴雷特食管热疗中的潜在用途。治疗时，一个充满肌肉等效材料的球囊包裹着天线。对天线（20 - 35毫米）的插入深度和线圈间距对产生的热分布的影响进行了表征。线圈间距为3.6毫米的35毫米螺旋天线在插入深度为40毫米时能实现均匀加热。据观察，天线产生的合成温度分布取决于在体模内的插入深度。对于所有研究的天线，插入深度越深，沿天线长度大约1/4和3/4处会出现两个高强度区域。相比之下，浅插入会导致主要是尖端加热，且在体模入口点有不理想的加热情况。然而，通过调整螺旋的线圈间距，在一系列插入深度范围内都能实现均匀的温度分布。
