Zhang Y, Joines W T, Oleson J R
Department of Electrical Engineering, Duke University, Durham, NC 27706.
Int J Hyperthermia. 1991 Jan-Feb;7(1):197-207. doi: 10.3109/02656739109004989.
Measurements made on the interstitial microwave antennas used for hyperthermia cancer therapy indicate that the heating patterns vary with the insertion depths (defined as the distance from the antenna tip to air-tissue interface). The antennas are made of thin coaxial cables with a radiation gap or gaps on the outer conductor. The antennas are inserted into small polypropylene catheters implanted in the tumour volume. This type of antenna may be simulated as an asymmetric dipole with one arm being the tip section consisting of the expanded extension of the inner conductor, and the other arm being the section of the outer conductor from the gap to the insertion point (air-tissue interface). We use four of the antennas to form a 2 cm x 2 cm array. The antennas are positioned on the corners of a 2 cm square. Measurements on both single antennas and multi-antenna arrays show that the maximum heating is not stationary with position along the antenna when the depth of insertion is changed. This paper investigates the theoretical prediction of the changes in heating patterns of interstitial microwave antennas at different insertion depths. Each of the antennas in the array is simulated as an asymmetric dipole. The SAR (specific absorption rate) is computed by using the insulated dipole theory. The temperature distribution in absence of perfusion is obtained through a thermal simulation routine to convert the SAR pattern into the temperature pattern. Excellent qualitative agreement is found between the theoretical heating pattern and the measured pattern in a non-perfused phantom on a 2 cm x 2 antenna array. Since the insertion depths of the interstitial antennas are different from patient to patient, it is recommended that simulation of the heating be done before treatments, to confirm the delivery of power to the target region.
对用于热疗癌症治疗的间质微波天线进行的测量表明,加热模式会随插入深度(定义为从天线尖端到空气 - 组织界面的距离)而变化。这些天线由细同轴电缆制成,外导体上有一个或多个辐射间隙。天线被插入植入肿瘤体积内的小型聚丙烯导管中。这种类型的天线可以模拟为不对称偶极子,其中一个臂是由内导体的扩展延伸部分组成的尖端部分,另一个臂是从间隙到插入点(空气 - 组织界面)的外导体部分。我们使用四个这样的天线组成一个2厘米×2厘米的阵列。天线位于一个2厘米见方的角上。对单个天线和多天线阵列的测量表明,当插入深度改变时,沿天线的位置上最大加热点并非固定不变。本文研究了间质微波天线在不同插入深度下加热模式变化的理论预测。阵列中的每个天线都模拟为不对称偶极子。通过使用绝缘偶极子理论计算比吸收率(SAR)。通过热模拟程序在无灌注情况下获得温度分布,以将SAR模式转换为温度模式。在2厘米×2厘米天线阵列的非灌注体模中,理论加热模式与测量模式之间发现了极好的定性一致性。由于间质天线的插入深度因患者而异,建议在治疗前进行加热模拟,以确认向目标区域输送的功率。