2'-Deoxy-5-fluorotubercidin.
作者信息
Seela Frank, Xu Kuiying, Eickmeier Henning
机构信息
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Barbarastrasse 7, 49069 Osnabrück, Germany.
出版信息
Acta Crystallogr C. 2005 Jun;61(Pt 6):o408-10. doi: 10.1107/S0108270105014265. Epub 2005 May 20.
PMID:15930698
Abstract
In the title compound, 4-amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine, C11H13FN4O3, the conformation of the glycosyl bond lies between anti and high anti [chi = -101.1 (3) degrees ]. The furanose moiety adopts the S-type sugar pucker (2T3), with P = 164.7 (3) degrees and tau = 40.1 (2) degrees . The extended structure is a three-dimensional hydrogen-bond network involving a C-H...F, two N-H...O and two O-H...O hydrogen bonds.
摘要
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