Ludbrook G L, Webb R K, Currie M, Watterson L M
Department of Anaesthesia and Intensive Care, University of Adelaide and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Qual Saf Health Care. 2005 Jun;14(3):e13. doi: 10.1136/qshc.2002.004416.
Myocardial ischaemia and infarction are significant perioperative complications which are associated with poor patient outcome. Anaesthetic practice should therefore focus, particularly in the at risk patient, on their prevention, their accurate detection, on the identification of precipitating factors, and on rapid effective management.
To examine the role of a previously described core algorithm "COVER ABCD-A SWIFT CHECK" supplemented by a specific sub-algorithm for myocardial ischaemia and infarction in the management of myocardial ischaemia and/or infarction occurring in association with anaesthesia.
The potential performance of this structured approach for each of the relevant incidents among the first 4000 reported to the Australian Incident Monitoring Study (AIMS) was compared with the actual management as reported by the anaesthetists involved.
Of the 125 incidents retrieved from the 4000 reports, 40 (1%) were considered to demonstrate myocardial infarction or ischaemia. The use of the structured approach described in this paper would have led to appropriate management in 90% of cases, with the remaining 10% requiring other sub-algorithms. It was considered that the application of this structured approach would have led to earlier recognition and/or better management of the problem in 45% of cases.
Close and continuous monitoring of patients at risk of myocardial ischaemia during anaesthesia is necessary, using optimal ECG lead configurations, but sensitivity of this monitoring is not 100%. Coronary vasodilatation with glyceryl trinitrate (GTN) should not be withheld when indicated and the early use of beta blocking drugs should be considered even with normal blood pressures and heart rates.
心肌缺血和梗死是严重的围手术期并发症,与患者预后不良相关。因此,麻醉实践应特别关注高危患者,重点在于预防、准确检测、识别诱发因素以及快速有效的处理。
研究先前描述的核心算法“COVER ABCD - A SWIFT CHECK”,并辅以针对心肌缺血和梗死的特定子算法,在麻醉相关心肌缺血和/或梗死管理中的作用。
将这种结构化方法对澳大利亚事件监测研究(AIMS)报告的前4000例相关事件中每例事件的潜在表现,与参与的麻醉医生报告的实际处理情况进行比较。
从4000份报告中检索到125例事件,其中40例(1%)被认为显示心肌梗死或缺血。本文所述结构化方法的应用在90%的病例中可实现恰当处理,其余10%需要其他子算法。据认为,这种结构化方法的应用在45%的病例中可使问题得到更早识别和/或更好处理。
麻醉期间对有心肌缺血风险的患者进行密切持续监测是必要的,采用最佳心电图导联配置,但这种监测的敏感性并非100%。有指征时不应停用硝酸甘油(GTN)进行冠状动脉扩张,即使血压和心率正常,也应考虑早期使用β受体阻滞剂。