Berseth C L, Ittmann P I
Department of Pediatrics, Mayo Clinic, Rochester, Minnesota 55095.
J Pediatr Gastroenterol Nutr. 1992 Feb;14(2):182-6. doi: 10.1097/00005176-199202000-00011.
In the fasting state, antral motor activity is similar in preterm and term infants, but the antral responses to feeding have not been compared in preterm and term infants. The purpose of this study was to use low-compliance, continuous perfusion manometry to compare antral and duodenal feeding responses in 13 preterm and nine term infants within the first 14 days of life. Confirming our previous studies, fasting antral motor activity was similar in preterm and term infants, but duodenal activity differed. Individual duodenal cluster activity was of shorter duration in preterm than in term infants (p less than 0.01). Motor activity in antrum and duodenum changed in both groups of infants in response to an intraduodenal milk infusion of 4 ml/kg/2 h; however, the nature of the change varied in the two regions. In term infants, the number of antral pressure waves, the duration of antral clusters, and the antral motility index decreased by one third or more during feeding when compared with fasting (all p less than 0.05). In contrast to the decrease in antral activity in response to feeding, the duodenal motility index and cluster activity increased significantly during feeding compared with fasting (both p less than 0.05). The divergent response of antral and duodenal motor activity in response to feedings was also seen in preterm infants. Antral pressure waves, the duration of antral clusters, and the antral motility index were decreased during feeding (all p less than 0.005 or less).(ABSTRACT TRUNCATED AT 250 WORDS)
在禁食状态下，早产和足月婴儿的胃窦运动活动相似，但尚未对早产和足月婴儿进食时胃窦的反应进行比较。本研究的目的是使用低顺应性连续灌注测压法，比较13例早产和9例足月婴儿出生后14天内胃窦和十二指肠对喂食的反应。与我们之前的研究一致，早产和足月婴儿的禁食胃窦运动活动相似，但十二指肠活动不同。早产婴儿的单个十二指肠簇状活动持续时间比足月婴儿短（p<0.01）。两组婴儿在十二指肠内输注4 ml/kg/2 h牛奶后，胃窦和十二指肠的运动活动均发生改变；然而，两个区域的变化性质不同。与禁食时相比，足月婴儿进食期间胃窦压力波数量、胃窦簇状活动持续时间和胃窦运动指数降低了三分之一或更多（均p<0.05）。与胃窦活动因进食而减少相反，与禁食相比，足月婴儿进食期间十二指肠运动指数和簇状活动显著增加（均p<0.05）。早产婴儿也出现了胃窦和十二指肠运动活动对喂食的不同反应。进食期间胃窦压力波、胃窦簇状活动持续时间和胃窦运动指数均降低（均p<0.005或更低）。（摘要截断于250字）
