Paap E, van der Net J, Helders P J M, Takken T
Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, Netherlands.
Arthritis Rheum. 2005 Jun 15;53(3):351-6. doi: 10.1002/art.21175.
To determine the physiologic response of the 6-minute walk test (6-mwt) in children with juvenile idiopathic arthritis (JIA).
Eighteen children with JIA (age 7-17 years; 6 boys, 12 girls) performed a 6-mwt and a maximal exercise test.
The physiologic response of the 6-mwt was on average between 80% and 85% of the peak values of heart rate and oxygen uptake (VO2peak) during the maximal exercise test, except for the minute ventilation, which had a mean percentage of 68.5%. Backward regression analysis showed that height and distance walked were the best predictors of VO2peak during cycling (R2 = 0.883, P < 0.001). During the 6-mwt, the difference between the first and second minute was significant in every variable, except for heart rate. The range of walking distance of children with JIA was comparable with that of healthy elderly people.
The physiologic response of the 6-mwt is at a submaximal, intense level of exercise. The course of the responses during the 6-mwt was normal. The 6-mwt can be regarded as a good test for measuring functional exercise capacity.
确定幼年特发性关节炎（JIA）患儿6分钟步行试验（6-MWT）的生理反应。
18名JIA患儿（年龄7 - 17岁；6名男孩，12名女孩）进行了6-MWT和最大运动试验。
6-MWT的生理反应平均为最大运动试验中心率和摄氧量（VO2peak）峰值的80%至85%，分钟通气量除外，其平均百分比为68.5%。向后回归分析表明，身高和步行距离是骑行时VO2peak的最佳预测指标（R2 = 0.883，P < 0.001）。在6-MWT期间，除心率外，每个变量在第一分钟和第二分钟之间的差异均具有显著性。JIA患儿的步行距离范围与健康老年人相当。
6-MWT的生理反应处于次最大强度的运动水平。6-MWT期间反应过程正常。6-MWT可被视为测量功能性运动能力的良好试验。
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