Crăiţoiu Stefania, Mocanu Carmen, Olaru Cristian, Rodica Mănescu
Clinica de Oftalmologie Craiova.
Oftalmologia. 2005;49(1):82-7.
The paper presents the vascular morphopathological lesions in diabetic retinopathy. We have initiated a comparative study between normal eye and ocular globes preserved from patients with diabetic retinopathy in different stages of evolution that were fixed and stained by classic histological techniques. We have focus on the histopathological examinations on arterial and venous morphology, in different retinal areas (central and peripheral). The vascular lesions were demonstrated at all types of vessels, capillaries, arterioles, venues and they were correlated with the evolutive stage of the disease. In principal they consisted in thickness of the basal membrane, the degeneration of pericytes, the proliferation of the endothelial cells, microaneurysms, neovessels and vascular hyalinization. The diabetes has increased the death of capillary cells and retinal neurons by a very near apoptosis process.
本文介绍了糖尿病视网膜病变中的血管形态病理学病变。我们启动了一项比较研究，比较正常眼睛与从处于不同演变阶段的糖尿病视网膜病变患者保存下来的眼球，这些眼球通过经典组织学技术进行固定和染色。我们重点关注了不同视网膜区域（中央和周边）动脉和静脉形态的组织病理学检查。在所有类型的血管、毛细血管、小动脉、小静脉中均发现了血管病变，且这些病变与疾病的演变阶段相关。主要病变包括基底膜增厚、周细胞变性、内皮细胞增殖、微动脉瘤、新生血管和血管玻璃样变。糖尿病通过非常接近凋亡的过程增加了毛细血管细胞和视网膜神经元的死亡。
