Versaci A, Macrí A, Scuderi G, Ascenti G, Crescenti F, Sfuncia G, Grosso M, Famulari C
Università degli Studi di Messina, Cattedra di Chirurgia d'Urgenza e dei Trapianti d'Organo.
G Chir. 2005 Mar;26(3):83-8.
Cystic tumours of the pancreas include a pathologically heterogeneous and rare group of tumours, which however have many common clinical features. They represent about 10% of pancreatic cystic lesions and 1% of all forms of neoplasms, thus having a certain relevance in organ surgery. So far two distinct categories of cystic tumours have been identified, the basically benign serous form and the potentially malign mucinous form, which may sometimes show malignant features as early as the diagnostic stage. As neoplasms are very difficult to interpret before operation, it is essential that diagnosis is as accurate as possible in order to streamline surgery, which will have to be carried out after histological tests have been performed on an adequate number of tumour sections. Basing on these two cases of cystic tumours of the pancreas and on current literature, the Authors discuss the effectiveness of imaging techniques, such as contrast echography, dosage of specific tumour markers and histological tests backed up by immunohistochemistry in identifying these neoplasms, in order to study this rare but interesting pathology more accurately.
胰腺囊性肿瘤包括一组病理上异质性且罕见的肿瘤,然而它们有许多共同的临床特征。它们约占胰腺囊性病变的10%,占所有肿瘤形式的1%,因此在器官手术中具有一定的相关性。到目前为止,已识别出两种不同类型的囊性肿瘤,基本为良性的浆液性类型和潜在恶性的黏液性类型,后者有时在诊断阶段就可能表现出恶性特征。由于肿瘤在手术前很难解读,因此必须尽可能准确地进行诊断,以便简化手术,而手术必须在对足够数量的肿瘤切片进行组织学检查后进行。基于这两例胰腺囊性肿瘤病例以及当前文献,作者讨论了诸如超声造影、特定肿瘤标志物检测以及免疫组织化学支持的组织学检查等成像技术在识别这些肿瘤方面的有效性,以便更准确地研究这种罕见但有趣的病理学。