Webber Adam P, Martin Jennifer L, Harker Judith O, Josephson Karen R, Rubenstein Laurence Z, Alessi Cathy A
Geriatric Research, Education and Clinical Center, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California, USA.
J Am Geriatr Soc. 2005 Jun;53(6):1017-22. doi: 10.1111/j.1532-5415.2005.53322.x.
To describe the prevalence, recognition, and persistence of depression in older adults undergoing postacute rehabilitation in a nursing home (NH) setting and to explore the effect of depression on rehabilitation outcomes.
Prospective cohort study.
One rehabilitative NH in the Los Angeles area.
One hundred fifty-eight patients (aged >/=65) admitted for postacute rehabilitation over a 9-month recruitment period.
Depression was assessed using the 15-item Geriatric Depression Scale (GDS-15) or the Cornell Scale for Depression (in participants with dementia). Medical records were reviewed for documentation of depression and antidepressant use before and during the rehabilitative NH stay. Rehabilitation process was assessed using total amount of successfully completed therapy (minutes). Rehabilitation outcome was assessed using the motor component of the Functional Independence Measure (mFIM). Measures were performed at admission and 2 months later.
Of the 646 potentially eligible patients admitted during the study, 158 consented, and 151 were screened for depression. Forty-two (27.8%) had depressive symptoms (GDS=6 or Cornell=5). Of these, only 15 had a documented diagnosis of depression, and 12 were receiving antidepressants. Depression was associated with longer NH stay but not with discharge mFIM score. Two months later, depression persisted in 24 participants and was associated with worse mFIM (55.5+/-22.7 vs 67.0+/-23.7, depressed vs nondepressed; P=.03).
Depression was common, underrecognized, and undertreated in these postacute rehabilitation patients. Depression generally persisted and was associated with worse functional status at 2-month follow-up.
描述在疗养院(NH)环境中接受急性后康复治疗的老年人抑郁症的患病率、识别情况及持续情况,并探讨抑郁症对康复结局的影响。
前瞻性队列研究。
洛杉矶地区的一家康复疗养院。
在9个月的招募期内,158名年龄≥65岁的急性后康复治疗入院患者。
使用15项老年抑郁量表(GDS-15)或康奈尔抑郁量表(用于痴呆患者)评估抑郁情况。查阅医疗记录,以记录在康复疗养院住院前及住院期间的抑郁情况和抗抑郁药使用情况。使用成功完成治疗的总量(分钟数)评估康复过程。使用功能独立性测量的运动部分(mFIM)评估康复结局。在入院时和2个月后进行测量。
在研究期间入院的646名潜在合格患者中,158名同意参与,151名接受了抑郁筛查。42名(27.8%)有抑郁症状(GDS=6或康奈尔=5)。其中,只有15名有记录在案的抑郁症诊断,12名正在接受抗抑郁药治疗。抑郁症与在疗养院住院时间较长有关,但与出院时的mFIM评分无关。2个月后,24名参与者的抑郁症状持续存在,且与较差的mFIM相关(抑郁组为55.5±22.7,非抑郁组为67.0±23.7;P=0.03)。
在这些急性后康复患者中,抑郁症很常见,但未得到充分认识和治疗。抑郁症通常会持续存在,且在2个月随访时与较差的功能状态相关。