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慢性疼痛中的精神病学:综述与更新

Psychiatry in chronic pain: a review and update.

作者信息

Sharp John, Keefe Brian

机构信息

Department of Psychiatry, Beth Israel Deaconess Medical Center 1101 Beacon Street Brookline, MA 02446, USA.

出版信息

Curr Psychiatry Rep. 2005 Jun;7(3):213-9. doi: 10.1007/s11920-005-0056-x.

DOI:10.1007/s11920-005-0056-x
PMID:15935136
Abstract

As the field of pain management nears the halfway point of the Congressionally declared "Decade of Pain Control and Research," the prevalence of chronic pain and disability related thereto continue to escalate. In the context of rising costs and suffering associated with persistent pain worldwide, the chronic pain research community has increasingly recognized and investigated the role of the cognitive and affective dimensions of pain. In this paper, the authors review psychologic aspects of pain, psychopathology in chronic pain syndromes, suicidality in this population, and the use of psychotropic medications for treatment in these patients. Where possible, the authors have outlined limitations of previous research in these areas, and have highlighted and described recent studies that have addressed these perceived shortcomings. The role of the psychiatrist in the treatment of patients with chronic pain is reviewed.

摘要

随着疼痛管理领域接近国会宣布的“疼痛控制与研究十年”的中点,慢性疼痛及其相关残疾的患病率持续上升。在全球范围内与持续性疼痛相关的成本上升和痛苦加剧的背景下,慢性疼痛研究界越来越认识到并研究疼痛的认知和情感维度的作用。在本文中,作者回顾了疼痛的心理学方面、慢性疼痛综合征中的精神病理学、该人群中的自杀倾向以及在这些患者中使用精神药物进行治疗的情况。作者尽可能概述了此前这些领域研究的局限性,并重点介绍和描述了针对这些明显不足的最新研究。本文还回顾了精神科医生在慢性疼痛患者治疗中的作用。

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Psychiatry in chronic pain: a review and update.慢性疼痛中的精神病学:综述与更新
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本文引用的文献

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Antidepressants and antiepileptic drugs for chronic non-cancer pain.用于慢性非癌性疼痛的抗抑郁药和抗癫痫药。
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Do the second-generation "atypical neuroleptics" have analgesic properties? A structured evidence-based review.第二代“非典型抗精神病药”具有镇痛特性吗?一项基于证据的结构化综述。
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A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.
复杂性区域疼痛综合征(CRPS)中的精神障碍:会诊联络精神科医生的作用。
Pain Res Manag. 2018 Oct 17;2018:2894360. doi: 10.1155/2018/2894360. eCollection 2018.
4
Previous Mental Disorders and Subsequent Onset of Chronic Back or Neck Pain: Findings From 19 Countries.先前的精神障碍与随后的慢性腰背或颈部疼痛发作:来自 19 个国家的调查结果。
J Pain. 2018 Jan;19(1):99-110. doi: 10.1016/j.jpain.2017.08.011. Epub 2017 Oct 12.
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Activation of Extracellular Signal-Regulated Kinases (ERK 1/2) in the Locus Coeruleus Contributes to Pain-Related Anxiety in Arthritic Male Rats.蓝斑中细胞外信号调节激酶(ERK 1/2)的激活促成了关节炎雄性大鼠与疼痛相关的焦虑。
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Pharmacological evaluation of Mallotus philippinensis (Lam.) Muell.-Arg. fruit hair extract for anti-inflammatory, analgesic and hypnotic activity.菲律宾叶下珠(Lam.)Muell.-Arg.果实毛提取物的抗炎、镇痛和催眠活性的药理学评价。
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Prevalence of pain-related single nucleotide polymorphisms in patients of African origin with sickle cell disease.非洲裔镰状细胞病患者中与疼痛相关的单核苷酸多态性的患病率。
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Mol Pain. 2015 Oct 9;11:63. doi: 10.1186/s12990-015-0066-6.
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An epigenetic hypothesis for the genomic memory of pain.一种关于疼痛的基因组记忆的表观遗传学假说。
Front Cell Neurosci. 2015 Mar 24;9:88. doi: 10.3389/fncel.2015.00088. eCollection 2015.
一项双盲、多中心试验,比较度洛西汀与安慰剂治疗伴或不伴重度抑郁症的纤维肌痛患者的疗效。
Arthritis Rheum. 2004 Sep;50(9):2974-84. doi: 10.1002/art.20485.
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Suicidal ideation, plans, and attempts in chronic pain patients: factors associated with increased risk.慢性疼痛患者的自杀意念、计划及企图:与风险增加相关的因素。
Pain. 2004 Sep;111(1-2):201-8. doi: 10.1016/j.pain.2004.06.016.
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Relationships between childhood maltreatment, adult health and psychiatric outcomes, and medical utilization.童年期虐待、成人健康与精神疾病结局以及医疗利用之间的关系。
J Clin Psychiatry. 2004;65 Suppl 12:10-5.
6
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Lost productive time and cost due to common pain conditions in the US workforce.美国劳动力因常见疼痛状况而损失的生产时间和成本。
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