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从研究实验室到乳酸菌工业应用的漫长而曲折的道路。

The long and winding road from the research laboratory to industrial applications of lactic acid bacteria.

作者信息

Pedersen Martin Bastian, Iversen Stig Lykke, Sørensen Kim Ib, Johansen Eric

机构信息

Research, Development and Application, Chr. Hansen A/S, 10-12 Bøge Allé, DK2970 Hørsholm, Denmark.

出版信息

FEMS Microbiol Rev. 2005 Aug;29(3):611-24. doi: 10.1016/j.femsre.2005.04.001.

DOI:10.1016/j.femsre.2005.04.001
PMID:15935510
Abstract

Research innovations are constantly occurring in universities, research institutions and industrial research laboratories. These are reported in the scientific literature and presented to the scientific community in various congresses and symposia as well as through direct contacts and collaborations. Conversion of these research results to industrially useful innovations is, however, considerably more complex than generally appreciated. The long and winding road from the research laboratory to industrial applications will be illustrated with two recent examples from Chr. Hansen A/S: the implementation in industrial scale of a new production technology based on respiration by Lactococcus lactis and the introduction to the market of L. lactis strains constructed using recombinant DNA technology.

摘要

研究创新在大学、研究机构和工业研究实验室中不断涌现。这些创新成果在科学文献中有所报道,并在各种大会和研讨会上以及通过直接接触与合作展示给科学界。然而,将这些研究成果转化为具有工业用途的创新要比一般认为的复杂得多。来自科汉森公司(Chr. Hansen A/S)的两个近期实例将说明从研究实验室到工业应用这条漫长而曲折的道路:基于乳酸乳球菌呼吸作用的一种新生产技术在工业规模上的实施,以及利用重组DNA技术构建的乳酸乳球菌菌株推向市场。

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