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来自墨西哥中部地区人群样本中15个基因座的STR数据。

STR data for 15 loci in a population sample from the central region of Mexico.

作者信息

Hernández-Gutiérrez S, Hernández-Franco P, Martínez-Tripp S, Ramos-Kuri M, Rangel-Villalobos H

机构信息

Laboratorio de Biología Molecular, Universidad Panamericana, México DF, Mexico; Departamento de Medicina Genómica y Toxicología Ambiental (IIB-UNAM)(2), México DF, Mexico.

出版信息

Forensic Sci Int. 2005 Jun 30;151(1):97-100. doi: 10.1016/j.forsciint.2004.09.080.

Abstract

A Mexican population sample was obtained from the central region of the country, including five states. Two hundred and eleven individuals were PCR-typed for 15 STR loci with the AmpFiota STR Identifiler PCR amplification kit (Applied Biosystems). The following autosomal markers were analyzed: D8S1179, D21S11, D7S820, CSF1PO, D19S433, vWA, TPOX, D18S51, D3S1358, TH01, D13S317, D16S539, D2S1338, D5S818, FGA and Amelogenin. Allele frequencies for each STR were estimated and compared to previous reports. Genotype distribution by locus and by two loci combination was in agreement with Hardy-Weinberg expectations for all 15 STRs. This STR system in Mexican-mestizos presented a combined probability of exclusion (PE) and discrimination (PD) longer than 99.999%.

摘要

从墨西哥中部地区(包括五个州)获取了一个人群样本。使用AmpFiota STR Identifiler PCR扩增试剂盒(应用生物系统公司)对211名个体进行了15个STR基因座的PCR分型。分析了以下常染色体标记:D8S1179、D21S11、D7S820、CSF1PO、D19S433、vWA、TPOX、D18S51、D3S1358、TH01、D13S317、D16S539、D2S1338、D5S818、FGA和Amelogenin。估计了每个STR的等位基因频率,并与之前的报告进行了比较。所有15个STR基因座的基因座基因型分布以及两个基因座组合的基因型分布均符合哈迪-温伯格预期。墨西哥混血儿中的这个STR系统显示出超过99.999%的联合排除概率(PE)和鉴别概率(PD)。

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