Stramer Brian, Martin Paul
Department of Physiology and Biochemistry, University of Bristol, UK.
Curr Biol. 2005 Jun 7;15(11):R425-7. doi: 10.1016/j.cub.2005.05.034.
The protective layer of the epidermis in Drosophila (cuticle) and mice (stratum corneum) are structurally unrelated. Yet new evidence suggests a conserved transcription factor, Grainyhead, controls both their development and the means by which both structures repair themselves.
果蝇(角质层)和小鼠(角质层)表皮的保护层在结构上并无关联。然而,新证据表明,一种保守的转录因子——颗粒头蛋白,控制着这两种保护层的发育以及它们自我修复的方式。