Checa Miguel A, Peiró Ricardo, Pascual Jara, Carreras Ramón
Department of Obstetrics and Gynaecology, Hospital del Mar, Autonomous University of Barcelona, Spain.
Eur J Obstet Gynecol Reprod Biol. 2005 Jul 1;121(1):38-45. doi: 10.1016/j.ejogrb.2004.09.016.
To assess differences between native Spanish and immigrant pregnant women in behaviour relating to the use of medications during pregnancy.
This cross-sectional study was carried out at the department of obstetrics and gynaecology of an acute-care teaching hospital in the city of Barcelona, Spain. A total of 1103 women who gave birth at the hospital during a 1-year period were enrolled in the study. Each woman was interviewed by a gynaecologist during her stay in hospital after delivery, with special reference to drug use during the pregnancy. Drug exposure was assigned to trimesters, and drugs were divided into therapeutic groups, while the women taking part were divided up by nationality, educational level, parity and age. Data were analysed using bivariate, multivariate, and cluster analyses.
Slightly over half (55.7%) of the women were native to Spain and 44.3% were immigrants of other nationalities. About a quarter, or 25.4%, of pregnant patients had not taken any drugs during their pregnancies. The most frequent drugs taken by the others were vitamins, which were used mostly by Spanish women, followed by analgesics, which were mostly taken by non-Spanish western women. The largest group who had taken folic acid was made up of non-Spanish western women, while the Asiatic patients had taken this in the smallest proportion of cases.
Spanish patients and immigrants from other western countries showed a similar behaviour in terms of drug intake during pregnancy, which was different from the behavioural patterns seen in pregnant patients from developing countries.
评估西班牙本国孕妇与移民孕妇在孕期用药行为方面的差异。
本横断面研究在西班牙巴塞罗那市一家急症护理教学医院的妇产科进行。共有1103名在1年期间内在该医院分娩的妇女纳入研究。每位妇女在产后住院期间由一名妇科医生进行访谈,特别提及孕期用药情况。药物暴露按孕期划分,药物分为治疗组,参与研究的妇女按国籍、教育水平、产次和年龄进行分组。数据采用双变量、多变量和聚类分析进行分析。
略超过一半(55.7%)的妇女是西班牙本国妇女,44.3%是其他国籍的移民。约四分之一(25.4%)的孕妇在孕期未服用任何药物。其他孕妇最常服用的药物是维生素,主要为西班牙妇女服用,其次是镇痛药,主要为非西班牙西方国家妇女服用。服用叶酸比例最高的群体是非西班牙西方国家妇女,而亚洲患者服用叶酸的比例最低。
西班牙患者和来自其他西方国家的移民在孕期用药方面表现出相似行为,这与发展中国家孕妇的行为模式不同。