转录终止因子Rho在新月柄杆菌中是必需的且受自身调控。
The transcription termination factor Rho is essential and autoregulated in Caulobacter crescentus.
作者信息
Italiani Valéria C S, Marques Marilis V
机构信息
Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, SP, Brazil.
出版信息
J Bacteriol. 2005 Jun;187(12):4290-4. doi: 10.1128/JB.187.12.4290-4294.2005.
Abstract
The impossibility of obtaining a rho null mutant and sensitivity to bicyclomycin have indicated that rho is essential for the viability of Caulobacter crescentus. Transcription gene fusions of sequences with serial deletions of the rho 5' untranslated region (5'-UTR) with a lacZ reporter gene indicated that rho is autoregulated at the level of attenuation of transcription in the 5'-UTR.
摘要
无法获得ρ零突变体以及对双环霉素敏感表明，ρ对于新月柄杆菌的生存能力至关重要。将具有ρ 5'非翻译区（5'-UTR）系列缺失的序列与lacZ报告基因进行转录基因融合表明，ρ在5'-UTR转录衰减水平上存在自我调节。
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