Ashida K, Imaizumi M, Isaka Y, Ishida M, Matsushita K, Nakayama H
Cardiovascular Division, Osaka National Hospital.
Nihon Ronen Igakkai Zasshi. 1992 Mar;29(3):202-6. doi: 10.3143/geriatrics.29.202.
Intraarterial infusion of thrombolytic agent is useful in the treatment of obstructive arterial diseases in various vessels. However, few studies have shown that this treatment is useful for aortic occlusion. We report the case with complete recanalization in the lower abdominal aorta following intraaortic infusion of a thrombolytic agent. A 59-year-old man was admitted because of weakness and pain in the bilateral lower limbs at rest. Aortography showed complete occlusion of the abdominal aorta proximal to the inferior mesenteric artery. Both external arteries were supplied via rich collaterals. He was treated by intraaortic urokinase infusion of 2,100,000 units. Total recanalization in the abdominal aorta and both common iliac arteries was obtained. Intraaortic infusion of urokinase was shown to be effective treatment of occlusion in the abdominal aorta.
动脉内输注溶栓剂对治疗各种血管的阻塞性动脉疾病有用。然而,很少有研究表明这种治疗对主动脉闭塞有用。我们报告一例在主动脉内输注溶栓剂后下腹主动脉完全再通的病例。一名59岁男性因双侧下肢静息时无力和疼痛入院。主动脉造影显示肠系膜下动脉近端的腹主动脉完全闭塞。双侧股动脉通过丰富的侧支供血。对其进行了210万单位的主动脉内尿激酶输注治疗。腹主动脉和双侧髂总动脉实现了完全再通。主动脉内输注尿激酶被证明是治疗腹主动脉闭塞的有效方法。