Treska V, Molácek J, Certík B, Kuntscher V, Ferda J
Chirurgicá klinika FN v Plzni.
Rozhl Chir. 2005 Mar;84(3):112-6.
Inflammatory aneurysm of the abdominal aorta is a rare disorder, affecting approximately 3-10% of the population with a diagnosis of the abdominal aortic aneurysm. The principal etiological agents of the disorder include bacterial microorganisms, primarily Salmonella, Staphylococcus aureus, and Escherichia coli. However, in many cases the etiology od the disorder remains unclear and, likely, autoimmune and genetic dispositions may play a certain role, as well. The principal diagnostic procedures include ultrasound, CT and MRI examinations. The principal therapeutic procedures include open resection of the inflammatory aneurysm with complete removal of the infectious tissue and its replacement by a prosthesis or a vascular allograft "in situ" or through an extraantomical reconstructive procedure. New procedures also include endovascular therapy which is technically much simpler, less demanding for a patient, however, it may leave a potential infectious focus in the organism with a risk of further septic complications to follow. Therefore, the authors recommend a strictly individual treatment strategy in each patient with this serious disorder. In case of positive cultivation bacteriological findings, extended (a minimum of 6 weeks) antibiotic therapy and regular, long-term patient follow-up with regular visits, are essential.
腹主动脉炎性动脉瘤是一种罕见疾病,约占腹主动脉瘤患者的3 - 10%。该疾病的主要病因包括细菌微生物,主要是沙门氏菌、金黄色葡萄球菌和大肠杆菌。然而,在许多情况下,该疾病的病因仍不明确,而且自身免疫和遗传因素可能也起一定作用。主要诊断方法包括超声、CT和MRI检查。主要治疗方法包括对炎性动脉瘤进行开放性切除,彻底清除感染组织,并用假体或血管同种异体移植物“原位”或通过解剖外重建手术进行替代。新的治疗方法还包括血管内治疗,该方法在技术上要简单得多,对患者的要求也较低,然而,它可能会在体内留下潜在的感染病灶,有发生进一步败血症并发症的风险。因此,作者建议对每一位患有这种严重疾病的患者采取严格的个体化治疗策略。如果细菌培养结果呈阳性,延长(至少6周)抗生素治疗以及对患者进行定期、长期的随访并定期复诊是必不可少的。