Stein G R, Jewell R C
Med J Aust. 1979 Jul 14;2(1):9-10. doi: 10.5694/j.1326-5377.1979.tb112647.x.
Primary hypothyroidism was diagnosed in a woman aged 33 years, with Down's syndrome and insulin-dependent diabetes mellitus after admission to hospital with hypoglycaemia. The diabetes was stabilized and treatment was commenced with L-thyroxine with a good clinical response. The patient's mother and older sister also had hypothyroidism and all three had no thyroid antibodies. The importance of diagnosing and treating primary hypothyroidism in adult patients with Down's syndrome is stressed even in the absence of thyroid antibodies.
一名33岁患有唐氏综合征和胰岛素依赖型糖尿病的女性因低血糖入院后被诊断为原发性甲状腺功能减退症。糖尿病病情得到稳定，开始使用左甲状腺素进行治疗，临床反应良好。患者的母亲和姐姐也患有甲状腺功能减退症，三人都没有甲状腺抗体。强调了即使在没有甲状腺抗体的情况下，对成年唐氏综合征患者诊断和治疗原发性甲状腺功能减退症的重要性。
