Kalef-Ezra J, Bozios G, Tsekeris P, Michalis L
Department of Medical Physics, University of Ioannina, 45110 Ioannina, Greece.
Radiat Prot Dosimetry. 2005;114(4):514-23. doi: 10.1093/rpd/nch496. Epub 2005 Jun 7.
Endovascular brachytherapy (EVBT) is an established treatment to reduce the probability of restenosis after a percutaneous coronary intervention. The purpose of this study was to assess (1) the manufacturer's stated dosimetric data for (90)Sr/(90)Y source trains to be used in EVBT and (2) the procedure-related radiation burden. The radiation fields in water around six (90)Sr/(90)Y source trains were studied using phantoms made of 'solid water' and MD55-2 radiochromic films. The water equivalence of the phantom material was tested by applying quantitative computed tomography. Thermoluminescence dosemeters were used to assess personal radiation burden and crosscheck the dose distribution along the source trains. Technical failure was observed in one source train and this train was excluded from analysis. The measured dose rate in water at 2 mm radial distance was on average 8% higher than the manufacture's stated value (range of measured to stated values 1.05--1.15). The dose rate decreased exponentially with radial distance between 2 and 6 mm. The dose rate in contact with the source viewing window of the delivery devices ranged between 0.5 and 7.5 mGy h(-1). Low-energy photons were the main contributors to personal dose.
血管内近距离放射治疗(EVBT)是一种已确立的用于降低经皮冠状动脉介入术后再狭窄概率的治疗方法。本研究的目的是评估:(1)用于EVBT的(90)Sr/(90)Y源串的制造商声明的剂量学数据;(2)与手术相关的辐射负担。使用由“固体水”和MD55 - 2放射变色胶片制成的体模,研究了六个(90)Sr/(90)Y源串周围水中的辐射场。通过应用定量计算机断层扫描来测试体模材料的水等效性。使用热释光剂量计评估个人辐射负担并交叉核对沿源串的剂量分布。在一个源串中观察到技术故障,该源串被排除在分析之外。在径向距离2 mm处水中测得的剂量率平均比制造商声明的值高8%(测量值与声明值的范围为1.05 - 1.15)。剂量率在2至6 mm之间随径向距离呈指数下降。与输送装置的源观察窗接触处的剂量率范围在0.5至7.5 mGy h(-1)之间。低能光子是个人剂量的主要贡献者。