Kirisits Christian, Hefner Alfred, Wexberg Paul, Pokrajac Boris, Glogar Dietmar, Pötter Richard, Georg Dietmar
Department of Radiotherapy and Radiobiology, Medical University of Vienna, AKH Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
Radiat Prot Dosimetry. 2004;108(3):237-45. doi: 10.1093/rpd/nch033.
In the last few years coronary endovascular brachytherapy using gamma- and beta-emitting radionuclides has been established as a standard treatment procedure to prevent restenosis after percutaneous coronary interventions. Direct measurements and calculations were made to determine personnel doses and organ doses of patients due to gamma rays of 192Ir and beta rays of 90Sr/90Y and 32P sources. In general, our results show that the dose levels are low compared with the X-ray exposure from angiography. The dose rate from bremsstrahlung at 1 m distance from a device containing a 90Sr/90Y source of 2.3 GBq is 4 micro Sv h(-1). The skin dose from beta rays during source transfer into and from the patient was estimated with the directional dose equivalent H'(0.07) of 10 micro Sv at 1 m distance from the catheter. By maintaining safe distances, the dose levels can be kept well within annual dose limits.
在过去几年中,使用发射γ射线和β射线的放射性核素进行冠状动脉血管内近距离放射治疗已成为预防经皮冠状动脉介入术后再狭窄的标准治疗程序。已进行直接测量和计算,以确定患者因192Ir的γ射线以及90Sr/90Y和32P源的β射线而受到的人员剂量和器官剂量。总体而言,我们的结果表明,与血管造影的X射线照射相比,剂量水平较低。距离含有2.3 GBq 90Sr/90Y源的装置1米处的轫致辐射剂量率为4微希沃特每小时(-1)。在源进出患者过程中,距导管1米处的β射线皮肤剂量是根据定向剂量当量H'(0.07)估算的,为10微希沃特。通过保持安全距离,剂量水平可保持在年度剂量限值之内。