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[对可能患有阿尔茨海默病患者记忆缺陷的认知]

[Awareness of memory deficits in patients with probable Alzheimer's disease].

作者信息

Retz-Junginger P, Supprian T, Retz W, Rösler M, Traue H C

机构信息

Institut für Gerichtliche Psychologie und Psychiatrie der Universität des Saarlandes, Homburg/Saar.

出版信息

Fortschr Neurol Psychiatr. 2005 Jun;73(6):327-32. doi: 10.1055/s-2004-830245.

Abstract

Thirty-eight patients with Alzheimer's disease were asked to give a qualitative (estimation of memory changes) and quantitative assessment of their own performance on memory tasks and also of their relatives' performance. Qualitative assessment showed to be independent from measured memory-deficits, while the precision of quantitative prediction of performance deteriorated with increased cognitive impairment. Cognitive impairment of the demented patients did not influence the prediction of the performance of their relatives. Both, qualitative and quantitative assessment of memory performance were influenced by premorbid coping-strategies. Patients, who were attributed to use strategies of cognitive avoidance, more often claimed to have no changes in memory function or over-estimated their memory performance. The results of this investigation reveal that methodological issues influence studies on the association of meta-cognitive abilities with the severity of dementia to a great extent. They also suggest that awareness of deficits should be based on a complex, multi-dimensional concept.

摘要

38名阿尔茨海默病患者被要求对自身在记忆任务中的表现以及亲属的表现进行定性(记忆变化评估)和定量评估。定性评估显示与测量出的记忆缺陷无关,而随着认知障碍加剧,表现的定量预测精度会下降。痴呆患者的认知障碍并不影响对其亲属表现的预测。记忆表现的定性和定量评估均受到病前应对策略的影响。那些被认为采用认知回避策略的患者,更常声称自己的记忆功能没有变化或高估了自己的记忆表现。这项调查结果表明,方法学问题在很大程度上影响了关于元认知能力与痴呆严重程度之间关联的研究。它们还表明,对缺陷的认知应基于一个复杂的、多维度的概念。

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