Darmstadt G L, Tunnessen W W, Swerer R J
Dept of Pediatrics and Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD.
Pediatrics. 1992 Jun;89(6 Pt 1):1095-8.
Eosinophilic pustular folliculitis is a cutaneous disorder that consists of recurrent crops of pruritic, sterile, papulopustules in a follicular distribution. In pediatric patients, EPF presents primarily in the scalp and is confused with several other more common dermatoses in children. The diagnosis of EPF rests on its inclusion in the differential diagnosis of papulopustular disorders, the recognition of the clinical presentation, and the presence of an eosinophilic infiltrate on biopsy. Treatment with midpotency topical corticosteroids has thus far met with modest success. This is the first report on EPF in the pediatric literature. As pediatricians become more aware of EPF as a distinct clinical entity and as our clinical experience and insight into the pathogenesis of EPF grows, perhaps more effective treatment modalities will be devised.
嗜酸性脓疱性毛囊炎是一种皮肤疾病,表现为反复出现的成批瘙痒性、无菌性丘疹脓疱,呈毛囊性分布。在儿科患者中,嗜酸性脓疱性毛囊炎主要出现在头皮,易与儿童其他几种更常见的皮肤病相混淆。嗜酸性脓疱性毛囊炎的诊断基于将其纳入丘疹脓疱性疾病的鉴别诊断、对临床表现的认识以及活检时出现嗜酸性浸润。到目前为止,使用中效外用糖皮质激素治疗取得了一定成效。这是儿科文献中关于嗜酸性脓疱性毛囊炎的首例报告。随着儿科医生越来越意识到嗜酸性脓疱性毛囊炎是一种独特的临床实体,以及我们对嗜酸性脓疱性毛囊炎发病机制的临床经验和认识不断增加,或许会设计出更有效的治疗方法。