Saylam Kurtipek Gulcan, Zekey Emre, Tuncez Akyurek Fatma, Demirbas Abdullah, Harmankaya İsmail
Department of Dermatology, Selcuk University Faculty of Medicine, Konya, Turkey.
Department of Dermatology, Selcuk Universitesi, Konya, Turkey.
J Cosmet Dermatol. 2022 Mar;21(3):1143-1146. doi: 10.1111/jocd.14161. Epub 2021 May 6.
Infantile eosinophilic pustular folliculitis (I-EPF) is a rare disease characterized by pruritic vesicles and sterile pustules on the erythematous surface of the scalp and facial localization, usually seen in the neonatal period. It is essential to show the presence of dense eosinophils in the diagnosis of pustules. Histopathological examination of the hair follicles by eosinophils infiltration is determined.
Here, we reported a 5-month-old baby boy diagnosed infantile eosinophilic pustular folliculitis.
A 5-month-old baby boy was consulted to our polyclinic by his family because of pustules on the scalp, face, and neck developing in two week after birth. In dermatological examination, the pustular lesions of 1-2 mm in diameter on the scalp, face, and neck on an erythematous background were determined.
There was no growth in the culture taken from the pustule. In the laboratory tests of the patient; upon detection of eosinophilia in the hemogram. The eosinophil count at the patient's first admission was 1.48 K/μl. (0.05 0.50). Eosinophil count was 0.02 K/μl after treatment. It was decreased. The patient was evaluated for other pustular dermatoses. In the differential diagnosis of the patient; causing bacterial/non-bacterial pustulosis were included. Bacterial culture was negative.
Eosinophilic folliculitis defines as a group of papulopustular diseases with unknown etiology characterized histologically by eosinophilic infiltrates. First, Ofuji reported a female patient with recurrent follicular pustules and peripheral eosinophilia as a variant of folliculitis in 1965. Its etiopathogenesis is not clearly known. In the differential diagnosis of EPF includes the other pustular lesions of the newborn such as erythematoxicum neonatarum, transient neonatal pustular dermatosis, infantile acropustulosis, scabies, dermatophytosis, and langerhans cell histiocytosis. Treatment options includes topical corticosteroids and calcineurin inhibitors, antihistamines, systemic antibacterial and anti-inflammatory agents, and dapson.
婴儿嗜酸性脓疱性毛囊炎（I-EPF）是一种罕见疾病，其特征为头皮和面部红斑表面出现瘙痒性水疱和无菌性脓疱，通常见于新生儿期。在脓疱诊断中显示密集嗜酸性粒细胞的存在至关重要。通过嗜酸性粒细胞浸润对毛囊进行组织病理学检查来确定。
在此，我们报告了一名诊断为婴儿嗜酸性脓疱性毛囊炎的5个月大男婴。
一名5个月大男婴因出生后两周头皮、面部和颈部出现脓疱，其家人带他到我们的门诊就诊。在皮肤科检查中，确定头皮、面部和颈部在红斑背景上有直径1-2毫米的脓疱性病变。
从脓疱中采集的培养物无生长。患者的实验室检查；血常规检测发现嗜酸性粒细胞增多。患者首次入院时嗜酸性粒细胞计数为1.48 K/μl。（0.05 - 0.50）。治疗后嗜酸性粒细胞计数为0.02 K/μl。有所下降。对患者进行了其他脓疱性皮肤病的评估。在患者的鉴别诊断中；包括引起细菌性/非细菌性脓疱病的疾病。细菌培养为阴性。
嗜酸性毛囊炎被定义为一组病因不明的丘疹脓疱性疾病，组织学上以嗜酸性粒细胞浸润为特征。1965年，Ofuji首次报告了一名患有复发性毛囊脓疱和外周嗜酸性粒细胞增多的女性患者，作为毛囊炎的一种变体。其发病机制尚不清楚。在嗜酸性脓疱性毛囊炎的鉴别诊断中包括新生儿的其他脓疱性病变，如新生儿毒性红斑、新生儿短暂性脓疱性皮肤病、婴儿肢端脓疱病、疥疮、皮肤癣菌病和朗格汉斯细胞组织细胞增多症。治疗选择包括外用糖皮质激素和钙调神经磷酸酶抑制剂、抗组胺药、全身性抗菌和抗炎药物以及氨苯砜。
