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骨质疏松症的预防:一项增加幼年类风湿性关节炎患儿钙摄入量的随机临床试验。

Prevention of osteoporosis: a randomized clinical trial to increase calcium intake in children with juvenile rheumatoid arthritis.

作者信息

Stark Lori J, Janicke David M, McGrath Ann M, Mackner Laura M, Hommel Kevin A, Lovell Daniel

机构信息

Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Division of Psychology, SEC-4, Cincinnati, Ohio 45229, USA.

出版信息

J Pediatr Psychol. 2005 Jul-Aug;30(5):377-86. doi: 10.1093/jpepsy/jsi061. Epub 2005 Feb 23.

DOI:10.1093/jpepsy/jsi061
PMID:15944165
Abstract

OBJECTIVE

To test the efficacy of a behavioral intervention (BI) compared to an enhanced standard of care (ESC) dietary counseling on increasing dietary calcium (Ca) intake in children with juvenile rheumatoid arthritis (JRA).

METHODS

Three-day food diaries collected at baseline and posttreatment were analyzed for Ca intake in 49 children with JRA randomly assigned to either BI or an ESC treatment.

RESULTS

Children in the BI (N = 25) demonstrated a significantly greater increase in average dietary Ca intake (M = 839) than children in the ESC (N = 24; M = 420) (F = 14.39; p < .001). Post hoc analysis revealed that children in both groups demonstrated significant gains in dietary Ca intake baseline to posttreatment. A significantly greater percentage of children in the BI (92%) attained the goal of 1500 mg/Ca at posttreatment compared to the ESC (17%), X2= 28.09; p < .001.

CONCLUSIONS

Behavioral intervention can have a positive impact on increasing dietary Ca intake. Future research will need to evaluate the maintenance of gains in dietary Ca intake following treatment cessation and the impact of increased Ca intake on bone mineral density.

摘要

目的

比较行为干预(BI)与强化标准护理(ESC)饮食咨询对提高青少年类风湿性关节炎(JRA)患儿膳食钙(Ca)摄入量的效果。

方法

对49例随机分配至BI或ESC治疗组的JRA患儿,分析其在基线和治疗后收集的3天食物日记中的钙摄入量。

结果

BI组(N = 25)患儿的平均膳食钙摄入量增加幅度(M = 839)显著大于ESC组(N = 24;M = 420)(F = 14.39;p < .001)。事后分析显示,两组患儿从基线到治疗后的膳食钙摄入量均有显著增加。与ESC组(17%)相比,BI组(92%)有显著更高比例的患儿在治疗后达到了1500 mg/Ca的目标,X2 = 28.09;p < .001。

结论

行为干预对增加膳食钙摄入量可产生积极影响。未来的研究需要评估停止治疗后膳食钙摄入量增加的维持情况以及钙摄入量增加对骨密度的影响。

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