Al-Shekhlee Amer, Lindenberg Judah R, Hachwi Rami N, Chelimsky Thomas C
Department of Neurology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA.
Clin Auton Res. 2005 Jun;15(3):219-22. doi: 10.1007/s10286-005-0282-7.
Postural tachycardia syndrome (POTS) is a fairly common condition that may or may not be associated with autonomic neuropathy. In a retrospective analysis, we compared two groups of patients based on clinical and autonomic criteria, those with POTS in isolation (POTS-Alone), and POTS with evidence of autonomic neuropathy (POTS-AN). Of 260 records reviewed, 57 patients met the criteria for POTS; 38 (67%) patients assigned to the POTS-Alone group and 19 (33%) patients assigned to the POTS-AN group. A decreased sweat output on the quantitative sudomotor axon reflex test is the most frequent abnormal finding in the POST-AN group suggesting sympathetic cholinergic neuropathy. Clinically, headache and gastrointestinal symptoms were more frequent among the POTS-AN group. Therefore, POTS may exist in isolation and may differ from those associated with AN.
体位性心动过速综合征（POTS）是一种相当常见的病症，可能与自主神经病变有关，也可能无关。在一项回顾性分析中，我们根据临床和自主神经标准比较了两组患者，即单纯性POTS患者（孤立性POTS）和有自主神经病变证据的POTS患者（POTS合并自主神经病变）。在审查的260份记录中，57例患者符合POTS标准；38例（67%）患者被归入孤立性POTS组，19例（33%）患者被归入POTS合并自主神经病变组。定量泌汗轴突反射试验中出汗量减少是POTS合并自主神经病变组最常见的异常发现，提示交感胆碱能神经病变。临床上，POTS合并自主神经病变组头痛和胃肠道症状更为常见。因此，POTS可能单独存在，且可能与合并自主神经病变的POTS不同。
