Michal M, Chlumská A, Povýsilová V
Department of Pathological Anatomy, University Hospital, Dobrany, Czechoslovakia.
Pathol Res Pract. 1992 Feb;188(1-2):199-204. doi: 10.1016/S0344-0338(11)81179-9.
Six cases of intranodal amianthoid myofibroblastomas are reported. Immunohistochemically the tumors were actin positive and S-100 protein and desmin negative. Intracytoplasmatic, actin-rich bodies, previously found to be a characteristic feature of this tumor, were identified as cytoplasmatic extensions filled with microfilaments at an ultrastructural level. Abortive vessel formation by the tumor cells and the proliferation of tumor cells centered on veins outside the capsule of the tumor in two of our cases indicated a close relationship between the intranodal palisaded myofibroblastoma and the musculature of vascular origin.
本文报告了6例淋巴结内石棉样肌成纤维细胞瘤。免疫组织化学显示，肿瘤肌动蛋白阳性，S-100蛋白和结蛋白阴性。胞质内富含肌动蛋白的小体，此前被认为是该肿瘤的特征性表现，在超微结构水平上被确定为充满微丝的胞质延伸。在我们的2例病例中，肿瘤细胞形成的异常血管以及肿瘤细胞围绕肿瘤包膜外静脉的增殖表明，淋巴结内栅栏状肌成纤维细胞瘤与血管起源的肌肉组织之间存在密切关系。
