Koseoglu R Dogan, Ozkan Namik, Filiz Nurper Onuk, Kayaoglu H Ayhan, Aydin Mehtap, Culha Emre N, Ersoy Omer F
Department of Pathology, School of Medicine, Gaziosmanpasa University, 60030 Tokat, Turkey.
Pathol Oncol Res. 2009 Jun;15(2):297-300. doi: 10.1007/s12253-008-9122-0. Epub 2008 Nov 8.
Intranodal palisaded myofibroblastoma (IPM) also called as intranodal hemorrhagic spindle cell tumor with amianthoid fibers is a distinctive and rare mesenchymal neoplasm of lymph nodes. This entity generally misdiagnosed as intranodal Kaposi's sarcoma or schwannoma in past. In contrast to Kaposi's sarcoma, it behaves in a benign fashion and does not need any further therapy except total surgical resection of the mass. This neoplasm has a great predilection for the inguinal region. The lesion presents typically as a unilateral, painless, solitary mass. To our knowledge, approximately 53 cases of IPM have been reported in the English-language literature. We present a 43-year-old-male patient with IPM and discuss histological, immunohistochemical features and pathogenesis of this rare benign neoplasm.
结内栅栏状肌成纤维细胞瘤(IPM),也称为伴有石棉样纤维的结内出血性梭形细胞瘤,是一种独特且罕见的淋巴结间叶性肿瘤。该实体过去通常被误诊为结内卡波西肉瘤或神经鞘瘤。与卡波西肉瘤不同,它表现为良性,除了对肿块进行完整手术切除外,无需任何进一步治疗。这种肿瘤极容易发生于腹股沟区。病变通常表现为单侧、无痛、孤立性肿块。据我们所知,英文文献中已报道约53例IPM。我们报告一例患有IPM的43岁男性患者,并讨论这种罕见良性肿瘤的组织学、免疫组化特征及发病机制。