Blanco Mario, Egozi Leon, Lubin Daniel, Poppiti Robert
The Arkadi M Rywlin MD, Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
Ann Diagn Pathol. 2005 Jun;9(3):157-9. doi: 10.1016/j.anndiagpath.2005.02.008.
Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm, accounting for only 0.1 % of all breast carcinomas. An intriguing factor of ACC in the breast is its good prognosis compared to ACC in other locations, mainly in the minor salivary glands. The incidence of axillary lymph node involvement is also very low compared to that of other breast tumors, and distant metastases are uncommon. We report the case of a 65-year-old woman with a 2-year history of a well-circumscribed breast nodule sonographically thought to be a lymph node which was later excised because of rapid growth. Histologic examination showed an adenoid cystic carcinoma with squamous differentiation originating in a fibroadenoma. A review of the literature reveals no previous report of such a case.
乳腺腺样囊性癌（ACC）是一种罕见的肿瘤，仅占所有乳腺癌的0.1%。乳腺ACC的一个有趣因素是，与其他部位（主要是小唾液腺）的ACC相比，其预后良好。与其他乳腺肿瘤相比，腋窝淋巴结受累的发生率也非常低，远处转移并不常见。我们报告一例65岁女性病例，该患者有一个边界清晰的乳腺结节，超声检查认为是一个淋巴结，因生长迅速后来被切除，病史2年。组织学检查显示起源于纤维腺瘤的伴有鳞状分化的腺样囊性癌。文献回顾未发现此前有此类病例的报道。
