Sammartino Gilberto, Tia Mariano, Marenzi Gaetano, di Lauro Alessandro Espedito, D'Agostino Elio, Claudio Pier Paolo
Dipartimento di Scienze Odontostomatologiche e Maxillofacciali, Universita' di Napoli Federico II, Italy.
J Oral Maxillofac Surg. 2005 Jun;63(6):766-70. doi: 10.1016/j.joms.2005.02.010.
The extraction of mesioangular impacted third molars may cause multiple periodontal defects at the distal root of the second molar. Platelet-rich plasma (PRP) is a material containing many autologous growth factors that may be used in repairing and preventing periodontal complications at the distal root of the second molar adjacent to the extracted third molar.
We analyzed the effects of autologous PRP on periodontal tissues after extraction of the third molar in 18 young patients (age, 21-26 years). Inclusion criteria were the presence of a pocket distal to the mandibular second molar with a probing depth>or=7.5 mm and a probing attachment level>or=6 mm.
We observed, at 12 weeks after surgery, a notable reduction in the probing depth and an improvement in the probing attachment level in those cases treated with PRP compared with the controls, as well as formation of new bone tissue in the bone defect.
We showed that PRP is effective in inducing and accelerating bone regeneration for the treatment of periodontal defects at the distal root of the mandibular second molar after surgical extraction of a mesioangular, deeply impacted mandibular third molar.
近中阻生第三磨牙的拔除可能会导致第二磨牙远中根出现多种牙周缺损。富血小板血浆（PRP）是一种含有多种自体生长因子的材料，可用于修复和预防拔除第三磨牙后相邻第二磨牙远中根的牙周并发症。
我们分析了18例年轻患者（年龄21 - 26岁）拔除第三磨牙后自体PRP对牙周组织的影响。纳入标准为下颌第二磨牙远中存在牙周袋，探诊深度≥7.5 mm且探诊附着水平≥6 mm。
术后12周时，我们观察到与对照组相比，接受PRP治疗的病例探诊深度显著降低，探诊附着水平有所改善，并且骨缺损处有新骨组织形成。
我们表明，PRP对于在下颌近中阻生、深度埋伏的第三磨牙手术拔除后诱导和加速下颌第二磨牙远中根牙周缺损的骨再生是有效的。
