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与重复使用左乙拉西坦相关的低钠血症。

Hyponatremia associated with repeated use of levetiracetam.

作者信息

Nasrallah Khalil, Silver Brian

机构信息

Department of Neurology, Henry Ford Hospital, Detroit, Michigan 48202, USA.

出版信息

Epilepsia. 2005 Jun;46(6):972-3. doi: 10.1111/j.1528-1167.2005.64004.x.

DOI:10.1111/j.1528-1167.2005.64004.x
PMID:15946344
Abstract

Levetiracetam (LEV) is increasingly used as adjunctive anticonvulsant therapy because of apparent low toxicity. Somnolence, asthenia, headache, dizziness, and nervousness are the most frequently reported side effects (1). We describe a patient, predisposed to the development of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), in whom hyponatremia developed after two challenges of LEV.

摘要

左乙拉西坦(LEV)因其明显的低毒性而越来越多地被用作辅助抗惊厥治疗。嗜睡、乏力、头痛、头晕和紧张是最常报告的副作用(1)。我们描述了一名易患抗利尿激素分泌异常综合征(SIADH)的患者,该患者在两次使用左乙拉西坦后出现了低钠血症。

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