Nasrallah Khalil, Silver Brian
Department of Neurology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Epilepsia. 2005 Jun;46(6):972-3. doi: 10.1111/j.1528-1167.2005.64004.x.
Levetiracetam (LEV) is increasingly used as adjunctive anticonvulsant therapy because of apparent low toxicity. Somnolence, asthenia, headache, dizziness, and nervousness are the most frequently reported side effects (1). We describe a patient, predisposed to the development of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), in whom hyponatremia developed after two challenges of LEV.
左乙拉西坦(LEV)因其明显的低毒性而越来越多地被用作辅助抗惊厥治疗。嗜睡、乏力、头痛、头晕和紧张是最常报告的副作用(1)。我们描述了一名易患抗利尿激素分泌异常综合征(SIADH)的患者,该患者在两次使用左乙拉西坦后出现了低钠血症。