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老年房室结折返性心动过速患者行射频导管消融术的疗效与安全性

Efficacy and safety of radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in the elderly.

作者信息

Rostock Thomas, Risius Tim, Ventura Rodolfo, Klemm Hanno U, Weiss Christian, Keitel Anna, Meinertz Thomas, Willems Stephan

机构信息

University Hospital Eppendorf, Department of Cardiology, D-20246 Hamburg, Germany.

出版信息

J Cardiovasc Electrophysiol. 2005 Jun;16(6):608-10. doi: 10.1111/j.1540-8167.2005.40717.x.

Abstract

INTRODUCTION

Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common regular supraventricular tachycardia in the general population as well as in elderly patients. The purpose of the study was to investigate the success and complication rate particularly regarding the induction of an atrioventricular (AV) block by radiofrequency (RF) ablation in elderly patients with and without a preexisting AV block.

METHODS AND RESULTS

Between February 1998 and July 2004, all patients with symptomatic AVNRT referred for slow-pathway ablation in our institution were included and divided into two groups: group 1 patients younger than 75 years (n = 508) and group 2 patients > or =75 years (n = 70). A preexisting prolonged PR interval was present in 17 (3.3%) patients of group 1 and in 26 (37%, P < 0.0001) patients of group 2. Following successful slow-pathway ablation (follow-up time group 1: 37 +/- 22, group 2: 37 +/- 24 months) no induction of an AV block was observed in group 2 but in four patients of group 1 (0.79%) a complete heart block was induced requiring a pacemaker implantation. In group 1, 15 (2.95%) patients with a recurrence of AVNRT were readmitted for a repeat ablation procedure. No recurrences occurred in group 2.

CONCLUSION

Despite a higher incidence of preexisting prolonged PR intervals slow-pathway ablation in elderly patients is both effective and safe and should be considered as the first line therapy also in this patient population.

摘要

引言

房室结折返性心动过速(AVNRT)是普通人群以及老年患者中最常见的规则性室上性心动过速。本研究的目的是调查在有或无既往房室传导阻滞的老年患者中,射频(RF)消融诱发房室(AV)阻滞的成功率和并发症发生率。

方法与结果

1998年2月至2004年7月,我院所有因症状性AVNRT前来接受慢径消融的患者被纳入研究,并分为两组:第1组患者年龄小于75岁(n = 508),第2组患者年龄≥75岁(n = 70)。第1组中有17例(3.3%)患者存在既往PR间期延长,第2组中有26例(37%,P < 0.0001)患者存在既往PR间期延长。慢径消融成功后(随访时间第1组:37±22个月,第2组:37±24个月),第2组未观察到诱发房室阻滞,但第1组有4例患者(0.79%)诱发了完全性心脏阻滞,需要植入起搏器。在第1组中,15例(2.95%)AVNRT复发的患者再次入院接受重复消融手术。第2组未出现复发情况。

结论

尽管既往PR间期延长的发生率较高,但老年患者的慢径消融既有效又安全,在这一患者群体中也应被视为一线治疗方法。

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