Coteur G, Danis B, Wantier P, Pernet Ph, Dubois Ph
Laboratoire de Biologie Marine (CP 160/15), Université Libre de Bruxelles, 50, Av. F. D. Roosevelt, B-1050 Bruxelles, Belgium.
Mar Pollut Bull. 2005 Nov;50(11):1295-302. doi: 10.1016/j.marpolbul.2005.04.038. Epub 2005 Jun 8.
In invertebrates, the phagocytosis exerted by immune cells constitutes the main line of internal defence against offending microorganisms. This study assessed during two consecutive years the phagocytic activity in seastars (Asterias rubens) collected in stations along the Belgian and Dutch coasts. The contamination of these seastars by metals and PCBs were measured in parallel. Increased phagocytic activities were found in seastars collected in the plume of the Scheldt river. This correlated with the contamination of seastars by metals, mainly Pb, but not with the contamination by the analysed PCB congeners. Furthermore, the relationship between phagocytosis and metal contamination was reproducible from one year to another. The possible mechanisms explaining this effect are discussed in light of a direct or indirect link between phagocytic activity and metal contamination of seastars.
在无脊椎动物中，免疫细胞发挥的吞噬作用构成了抵御有害微生物的主要内在防御防线。本研究连续两年评估了在比利时和荷兰沿海各站点采集的海星（赭色海星）的吞噬活性。同时还测量了这些海星中金属和多氯联苯的污染情况。在斯海尔德河河口羽流区域采集的海星中发现吞噬活性增强。这与海星被金属污染有关，主要是铅污染，但与所分析的多氯联苯同系物污染无关。此外，吞噬作用与金属污染之间的关系在不同年份具有可重复性。根据吞噬活性与海星金属污染之间的直接或间接联系，讨论了解释这种效应的可能机制。
