Miller M D, Paradis C F, Houck P R, Mazumdar S, Stack J A, Rifai A H, Mulsant B, Reynolds C F
Department of Psychiatry, University of Pittsburgh, PA.
Psychiatry Res. 1992 Mar;41(3):237-48. doi: 10.1016/0165-1781(92)90005-n.
Reliable quantitative ratings of chronic medical illness burden have proved to be difficult in geropsychiatric practice and research. Thus, the purpose of the study was to demonstrate the feasibility and reliability of a modified version of the Cumulative Illness Rating Scale (CIRS; Linn et al., 1968) in providing quantitative ratings of chronic illness burden. The modified CIRS was operationalized with a manual of guidelines geared toward the geriatric patient and for clarity was designated the CIRS(G). A total of 141 elderly outpatient subjects (two medical clinic groups of 20 each, 45 recurrent depressed subjects, 21 spousally bereaved subjects, and 35 healthy controls) received comprehensive physical examinations, reviews of symptoms, and laboratory testing. These data were then used by nurse practitioners, physician's assistants, and geriatric psychiatrists to compute CIRS(G) ratings of chronic illness burden. As hypothesized, analysis of variance demonstrated significant differences among groups with respect to total medical illness burden, which was highest among medical clinic patients and lowest in control subjects. Good interrater reliability (i.e., intraclass correlations of 0.78 and 0.88 in a subsample of 10 outpatients and a separate group of 10 inpatients, respectively) was achieved for CIRS(G) total scores. Among medical clinic patients, a significant correlation was found, as expected, between CIRS(G) chronic illness burden and capability as quantified by the Older Americans Activities of Daily Living Scale; and between CIRS(G) scores and physicians' global estimates of medical burden. Finally, with repeated measures of illness burden approximately 1 year from symptom baseline, significant rises were detected, as expected. The current data suggest that the CIRS(G) can be successfully applied in medically and psychiatrically impaired elderly subjects, with good interrater reliability and face validity (credibility).
在老年精神病学实践和研究中,可靠地对慢性疾病负担进行定量评估已被证明是困难的。因此,本研究的目的是证明累积疾病评定量表(CIRS;Linn等人,1968年)的一个修改版本在提供慢性疾病负担定量评估方面的可行性和可靠性。修改后的CIRS通过一本针对老年患者的指南手册进行操作,并为清晰起见被指定为CIRS(G)。共有141名老年门诊受试者(两个医疗诊所组,每组20人,45名复发性抑郁症患者,21名丧偶者,以及35名健康对照)接受了全面的体格检查、症状复查和实验室检测。然后,执业护士、医师助理和老年精神病医生利用这些数据来计算CIRS(G)慢性疾病负担评分。正如所假设的,方差分析表明,各组在总医疗疾病负担方面存在显著差异,医疗诊所患者的负担最高,对照组最低。CIRS(G)总分实现了良好的评分者间信度(即在10名门诊患者子样本和另一组10名住院患者中,组内相关系数分别为0.78和0.88)。在医疗诊所患者中,正如预期的那样,发现CIRS(G)慢性疾病负担与由美国老年人日常生活活动量表量化的能力之间存在显著相关性;以及CIRS(G)评分与医生对医疗负担的总体估计之间存在显著相关性。最后,在从症状基线起约1年的疾病负担重复测量中,如预期的那样检测到了显著上升。目前的数据表明,CIRS(G)可以成功应用于患有医学和精神疾病的老年受试者,具有良好的评分者间信度和表面效度(可信度)。