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COX 2 inhibitors, traditional NSAIDs, and the heart.

作者信息

Jüni Peter, Reichenbach Stephan, Egger Matthias

出版信息

BMJ. 2005 Jun 11;330(7504):1342-3. doi: 10.1136/bmj.330.7504.1342.

DOI:10.1136/bmj.330.7504.1342
PMID:15947376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC558270/
Abstract
摘要

相似文献

1
COX 2 inhibitors, traditional NSAIDs, and the heart.环氧化酶-2抑制剂、传统非甾体抗炎药与心脏
BMJ. 2005 Jun 11;330(7504):1342-3. doi: 10.1136/bmj.330.7504.1342.
2
[Selective COX-2 inhibitors--side effects in relation to non-specific non-steroidal anti-inflammatory drugs].[选择性环氧化酶-2抑制剂——与非特异性非甾体抗炎药相关的副作用]
Ugeskr Laeger. 2004 Dec 6;166(50):4581-4.
3
COX-2 inhibitors: better than traditional NSAIDs? Vioxx and Celebrex may be no less risky than NSAIDs.环氧化酶-2(COX-2)抑制剂:比传统非甾体抗炎药更好吗?万络和西乐葆的风险可能并不亚于非甾体抗炎药。
Health News. 2002 Aug;8(8):5.
4
Adverse Drug Events Involving COX-2 Inhibitors.涉及COX-2抑制剂的药物不良事件。
Ann Pharmacother. 2003 Sep;37(9):1203-13. doi: 10.1345/aph.1A212.
5
New NSAIDs and gastroduodenal damage.新型非甾体抗炎药与胃十二指肠损伤
Ital J Gastroenterol. 1996 Dec;28 Suppl 4:28-9.
6
Risk of gastrointestinal effects with COX-2 inhibitors and NSAIDs: COX-2 inhibitors were thought of as a safe option.COX-2抑制剂和非甾体抗炎药引起胃肠道不良反应的风险:COX-2抑制剂曾被认为是一种安全的选择。
BMJ. 2005 Dec 17;331(7530):1474. doi: 10.1136/bmj.331.7530.1474-b.
7
Are selective COX 2 inhibitors superior to traditional NSAIDs? Both the CLASS and VIGOR trials support the COX 2 hypothesis.选择性环氧化酶-2(COX-2)抑制剂是否优于传统非甾体抗炎药(NSAIDs)?CLASS试验和VIGOR试验均支持COX-2假说。
BMJ. 2002 Jul 20;325(7356):161; author reply 161.
8
Standard NSAIDs vs. COX-2 inhibitors.标准非甾体抗炎药与环氧化酶-2抑制剂对比
Johns Hopkins Med Lett Health After 50. 2002 Jan;13(11):3.
9
Are selective COX 2 inhibitors superior to traditional NSAIDs? Pharmacia's response to editorial.选择性环氧化酶-2抑制剂是否优于传统非甾体抗炎药?法玛西亚公司对一篇社论的回应。
BMJ. 2002 Jul 20;325(7356):161; author reply 161.
10
By the way, doctor. I'm confused. I've read your articles about heart disease being caused by inflammation. If the COX-2 drugs are anti-inflammatory, why do they seem to make heart disease worse, not better?顺便问一下,医生。我很困惑。我读了你关于心脏病是由炎症引起的文章。如果COX - 2药物是抗炎的,为什么它们似乎会使心脏病恶化,而不是好转呢?
Harv Health Lett. 2005 May;30(7):8.

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Invest New Drugs. 2017 Apr;35(2):158-165. doi: 10.1007/s10637-016-0417-9. Epub 2016 Dec 26.
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Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor.环氧补骨脂素对巨噬细胞移动抑制因子的抗炎新活性:抑制巨噬细胞移动抑制因子的互变异构酶和促炎活性。
J Biol Chem. 2012 Jul 13;287(29):24844-61. doi: 10.1074/jbc.M112.341321. Epub 2012 May 29.
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Trials. 2011 Nov 23;12:249. doi: 10.1186/1745-6215-12-249.
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Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model.5-羟色胺受体 2A/C 参与电针对骨关节炎大鼠模型疼痛的抑制作用。
Evid Based Complement Alternat Med. 2011;2011:619650. doi: 10.1093/ecam/neq016. Epub 2011 Jan 9.
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Population impact of regulatory activity restricting prescribing of COX-2 inhibitors: ecological study.限制环氧化酶-2 抑制剂处方的监管活动对人群的影响:生态研究。
Br J Clin Pharmacol. 2009 Nov;68(5):752-64. doi: 10.1111/j.1365-2125.2009.03500.x.
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Evaluation of inhibitory activities of plant extracts on production of LPS-stimulated pro-inflammatory mediators in J774 murine macrophages.评价植物提取物对 J774 鼠巨噬细胞产生脂多糖刺激的促炎介质的抑制活性。
Mol Cell Biochem. 2010 Mar;336(1-2):127-35. doi: 10.1007/s11010-009-0263-6. Epub 2009 Oct 8.

本文引用的文献

1
Differences in outcomes of patients with congestive heart failure prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs: population based study.充血性心力衰竭患者使用塞来昔布、罗非昔布或非甾体抗炎药的疗效差异:基于人群的研究。
BMJ. 2005 Jun 11;330(7504):1370. doi: 10.1136/bmj.330.7504.1370.
2
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.服用环氧化酶-2抑制剂或传统非甾体抗炎药患者的心肌梗死风险:基于人群的巢式病例对照分析
BMJ. 2005 Jun 11;330(7504):1366. doi: 10.1136/bmj.330.7504.1366.
3
Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery.心脏手术后COX-2抑制剂帕瑞昔布和伐地昔布的并发症。
N Engl J Med. 2005 Mar 17;352(11):1081-91. doi: 10.1056/NEJMoa050330. Epub 2005 Feb 15.
4
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention.在一项预防结直肠腺瘤的临床试验中与塞来昔布相关的心血管风险。
N Engl J Med. 2005 Mar 17;352(11):1071-80. doi: 10.1056/NEJMoa050405. Epub 2005 Feb 15.
5
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial.一项结直肠腺瘤化学预防试验中与罗非昔布相关的心血管事件。
N Engl J Med. 2005 Mar 17;352(11):1092-102. doi: 10.1056/NEJMoa050493. Epub 2005 Feb 15.
6
Risk of cardiovascular events and rofecoxib: cumulative meta-analysis.心血管事件风险与罗非昔布:累积荟萃分析
Lancet. 2004;364(9450):2021-9. doi: 10.1016/S0140-6736(04)17514-4.
7
Better reporting of harms in randomized trials: an extension of the CONSORT statement.随机试验中不良事件的更好报告:CONSORT声明的扩展
Ann Intern Med. 2004 Nov 16;141(10):781-8. doi: 10.7326/0003-4819-141-10-200411160-00009.
8
Lessons from the withdrawal of rofecoxib.罗非昔布撤市的教训。
BMJ. 2004 Oct 16;329(7471):867-8. doi: 10.1136/bmj.329.7471.867.
9
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial.在治疗性关节炎研究和胃肠道事件试验(TARGET)中罗美昔布与萘普生和布洛芬的比较:心血管结局的随机对照试验
Lancet. 2004;364(9435):675-84. doi: 10.1016/S0140-6736(04)16894-3.
10
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic.环氧化酶:新形式、新抑制剂及临床经验教训
FASEB J. 2004 May;18(7):790-804. doi: 10.1096/fj.03-0645rev.