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腹腔镜前列腺癌根治术后围手术期并发症的分类及趋势

Classification and trends of perioperative morbidities following laparoscopic radical prostatectomy.

作者信息

Gonzalgo Mark L, Pavlovich Christian P, Trock Bruce J, Link Richard E, Sullivan Wendy, Su Li-Ming

机构信息

Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.

出版信息

J Urol. 2005 Jul;174(1):135-9; discussion 139. doi: 10.1097/01.ju.0000161607.04334.26.

Abstract

PURPOSE

We classified and assessed trends in the incidence, severity and management of perioperative morbidity following laparoscopic radical prostatectomy (LRP).

MATERIALS AND METHODS

We retrospectively reviewed the records of 250 patients with clinically localized prostate cancer who underwent transperitoneal LRP, as performed by 2 surgeons (CPP and LMS), between April 2001 and March 2004. The Clavien classification system was used to grade complications for cases completed laparoscopically.

RESULTS

In the 246 cases completed laparoscopically 20 grade II, 12 grade III and 2 grade IV complications were noted during a mean followup of 13.7 months (overall complication rate 13.8%). Median hospital stay was 2 days (range 2 to 8) and median duration of bladder catheterization was 10 days (range 3 to 36). Postoperative ileus that prolonged hospital stay was the most frequent complication and it occurred in 8 patients (3.3%). Seven patients required blood transfusion (2.8%). Bladder neck contracture was observed in 3 patients (1.2%). A total of 11 complications occurred in the first 50 cases, while 12, 6, 8 and 1 occurred in cases 51 to 100, 101 to 150, 151 to 200 and 201 to 250, respectively.

CONCLUSIONS

Perioperative complications following LRP are mostly self-limited and grade II or III (94.1%). The incidence of complications and need for conversion to open radical prostatectomy decreased with experience. Uniform reporting and grading of surgical complications via a standardized classification system may permit more meaningful comparisons among different centers and surgical techniques.

摘要

目的

我们对腹腔镜根治性前列腺切除术(LRP)后围手术期发病率的发生率、严重程度及处理方式进行了分类和评估。

材料与方法

我们回顾性分析了2001年4月至2004年3月期间由两位外科医生(CPP和LMS)实施经腹LRP的250例临床局限性前列腺癌患者的记录。采用Clavien分类系统对腹腔镜完成的病例并发症进行分级。

结果

在246例腹腔镜完成的病例中,平均随访13.7个月期间,发现20例Ⅱ级、12例Ⅲ级和2例Ⅳ级并发症(总体并发症发生率13.8%)。中位住院时间为2天(范围2至8天),中位膀胱导尿时间为10天(范围3至36天)。延长住院时间的术后肠梗阻是最常见的并发症,8例患者发生(3.3%)。7例患者需要输血(2.8%)。3例患者观察到膀胱颈挛缩(1.2%)。前50例病例共发生11例并发症,而第51至100例、101至150例、151至200例和201至250例分别发生12例、6例、8例和1例。

结论

LRP后的围手术期并发症大多为自限性,Ⅱ级或Ⅲ级(94.1%)。随着经验的增加,并发症发生率及转为开放性根治性前列腺切除术的需求降低。通过标准化分类系统对手术并发症进行统一报告和分级,可能有助于不同中心和手术技术之间进行更有意义的比较。

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