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缩窄性心包炎和高度房室传导阻滞作为心脏B细胞淋巴瘤的首发表现

Pericarditis constrictiva and high-degree atrioventricular block as a first manifestation of a cardiac B-cell lymphoma.

作者信息

Engelen Markus A, Bruch Christian, Buerger Horst, Weckesser Matthias, Hoffmeier Andreas

机构信息

Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany.

出版信息

J Am Soc Echocardiogr. 2005 Jun;18(6):694. doi: 10.1016/j.echo.2004.08.023.

DOI:10.1016/j.echo.2004.08.023
PMID:15947778
Abstract

Primary cardiac lymphoma is an extremely rare extranodal non-Hodgkin's lymphoma, exclusively located in the heart and/or the pericardium with no evidence of extracardiac dissemination. In this report, we describe a cardiac B-cell lymphoma arising in a 70-year-old woman who presented to the hospital with heart failure symptoms and a high-degree atrioventricular block of unknown origin. Echocardiography revealed a massive infiltrative thickening of the atrial septum, the aortic root, and the pericardium. Pulsed wave and Doppler tissue findings were highly suggestive for pericarditis constrictiva. Positron emission tomography showed unusually strong metabolic activity in the atrial septum, both atria, and the entire pericardium. Suggested malignoma was confirmed by the pericardial biopsy specimens, which revealed a high-grade diffuse CD20+ B-cell lymphoma.

摘要

原发性心脏淋巴瘤是一种极其罕见的结外非霍奇金淋巴瘤,仅位于心脏和/或心包,无心脏外播散证据。在本报告中,我们描述了一名70岁女性发生的心脏B细胞淋巴瘤,该患者因心力衰竭症状和不明原因的高度房室传导阻滞入院。超声心动图显示房间隔、主动脉根部和心包有大量浸润性增厚。脉冲波和多普勒组织检查结果高度提示缩窄性心包炎。正电子发射断层扫描显示房间隔、双心房和整个心包有异常强烈的代谢活性。心包活检标本证实为恶性肿瘤,显示为高级别弥漫性CD20+B细胞淋巴瘤。

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