Viganò Sara Maria, Edefonti Alberto, Ferraresso Mariano, Ranzi Maria Luisa, Grossi Paolo, Righini Andrea, Rusconi Roberto, Santambrogio Luigi, Ghio Luciana
ICP Pediatric Nephrology, Dialysis and Transplantation Unit, Milan, Italy.
Pediatr Nephrol. 2005 Aug;20(8):1186-8. doi: 10.1007/s00467-005-1978-6. Epub 2005 Jun 10.
Brain abscesses caused by Nocardia are rare, but it is very important to detect and treat them early because the associated mortality is 3 times higher than that associated with other bacterial brain abscesses. This infection is prevalent among adults on long-term immunosuppressive therapy; we report the case of a male kidney transplant recipient aged 12.7 years who developed early multiple Nocardia-induced brain abscesses that were successfully treated with linezolid, a novel antibiotic therapy.
诺卡菌引起的脑脓肿较为罕见,但早期检测和治疗非常重要,因为其相关死亡率比其他细菌性脑脓肿高出3倍。这种感染在接受长期免疫抑制治疗的成年人中很常见;我们报告了一例12.7岁男性肾移植受者的病例,该患者早期出现了多发性诺卡菌引起的脑脓肿,并通过新型抗生素利奈唑胺成功治愈。