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一名儿科肾移植受者因鼻疽诺卡菌感染导致多发性脑脓肿的成功医学治疗。

Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient.

作者信息

Viganò Sara Maria, Edefonti Alberto, Ferraresso Mariano, Ranzi Maria Luisa, Grossi Paolo, Righini Andrea, Rusconi Roberto, Santambrogio Luigi, Ghio Luciana

机构信息

ICP Pediatric Nephrology, Dialysis and Transplantation Unit, Milan, Italy.

出版信息

Pediatr Nephrol. 2005 Aug;20(8):1186-8. doi: 10.1007/s00467-005-1978-6. Epub 2005 Jun 10.

DOI:10.1007/s00467-005-1978-6
PMID:15947983
Abstract

Brain abscesses caused by Nocardia are rare, but it is very important to detect and treat them early because the associated mortality is 3 times higher than that associated with other bacterial brain abscesses. This infection is prevalent among adults on long-term immunosuppressive therapy; we report the case of a male kidney transplant recipient aged 12.7 years who developed early multiple Nocardia-induced brain abscesses that were successfully treated with linezolid, a novel antibiotic therapy.

摘要

诺卡菌引起的脑脓肿较为罕见，但早期检测和治疗非常重要，因为其相关死亡率比其他细菌性脑脓肿高出3倍。这种感染在接受长期免疫抑制治疗的成年人中很常见；我们报告了一例12.7岁男性肾移植受者的病例，该患者早期出现了多发性诺卡菌引起的脑脓肿，并通过新型抗生素利奈唑胺成功治愈。

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Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient.一名儿科肾移植受者因鼻疽诺卡菌感染导致多发性脑脓肿的成功医学治疗。
Pediatr Nephrol. 2005 Aug;20(8):1186-8. doi: 10.1007/s00467-005-1978-6. Epub 2005 Jun 10.
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Successful long-term treatment with linezolid for disseminated infection with multiresistant Nocardia farcinica.利奈唑胺成功用于长期治疗多重耐药鼻疽诺卡菌的播散性感染。
Infection. 2008 Aug;36(4):389-91. doi: 10.1007/s15010-008-7236-7. Epub 2008 Jul 15.
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Nocardiosis in transplant recipients.移植受者中的奴卡菌病。
Eur J Clin Microbiol Infect Dis. 2014 May;33(5):689-702. doi: 10.1007/s10096-013-2015-5. Epub 2013 Nov 23.
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First case of cerebral abscess due to a novel Nocardia species in an immunocompromised patient.首例免疫功能低下患者新型奴卡菌引起的脑脓肿。

本文引用的文献

1
Nocardiosis: a review.诺卡菌病综述
Int J Infect Dis. 2003 Dec;7(4):243-50. doi: 10.1016/s1201-9712(03)90102-0.
2
Nocardial brain abscess in a renal transplant recipient.
Clin Imaging. 2003 Sep-Oct;27(5):321-4. doi: 10.1016/s0899-7071(02)00554-5.
3
Multi-system Infection with Nocardia farcinica-therapy with linezolid and minocycline.
J Infect. 2003 Apr;46(3):199-202. doi: 10.1053/jinf.2002.1122.
4
J Clin Microbiol. 2013 Feb;51(2):696-700. doi: 10.1128/JCM.00762-12. Epub 2012 Dec 5.
4
Clinical update on linezolid in the treatment of Gram-positive bacterial infections.利奈唑胺治疗革兰氏阳性菌感染的临床最新进展。
Infect Drug Resist. 2012;5:87-102. doi: 10.2147/IDR.S25890. Epub 2012 Jun 25.
5
Disseminated Nocardia farcinica: literature review and fatal outcome in an immunocompetent patient.播散性星型诺卡菌感染：免疫功能正常患者的文献复习和致死结局。
Surg Infect (Larchmt). 2012 Jun;13(3):163-70. doi: 10.1089/sur.2011.012. Epub 2012 May 21.
6
Nocardia brain abscess in a liver transplant recipient.一名肝移植受者发生诺卡菌性脑脓肿。
J Korean Neurosurg Soc. 2011 Oct;50(4):396-8. doi: 10.3340/jkns.2011.50.4.396. Epub 2011 Oct 31.
7
Update and actual trends on bacterial infections following liver transplantation.肝移植术后细菌感染的最新情况及实际趋势
World J Gastroenterol. 2008 Aug 28;14(32):4977-83. doi: 10.3748/wjg.14.4977.
Report of human nocardiosis in Italy between 1993 and 1997.
1993年至1997年意大利人体诺卡菌病报告。
Eur J Epidemiol. 2001;17(11):1019-22. doi: 10.1023/a:1020010826300.
5
Oxazolidinone antibiotics.恶唑烷酮类抗生素
Lancet. 2001 Dec 8;358(9297):1975-82. doi: 10.1016/S0140-6736(01)06964-1.
6
In vitro activities of linezolid against multiple Nocardia species.利奈唑胺对多种诺卡菌属细菌的体外活性。
Antimicrob Agents Chemother. 2001 Apr;45(4):1295-7. doi: 10.1128/AAC.45.4.1295-1297.2001.
7
Fatal disseminated Nocardia farcinica infection in a renal transplant recipient.一名肾移植受者发生致命性播散性鼻疽诺卡菌感染。
Pediatr Nephrol. 2000 Feb;14(2):111-3. doi: 10.1007/s004670050023.
8
Disseminated and cerebral infection due to Nocardia farcinica: diagnosis by blood culture and cure with antibiotics alone.豚鼠诺卡菌引起的播散性和脑部感染：通过血培养诊断并仅用抗生素治愈。
Clin Infect Dis. 1996 Nov;23(5):1165-7. doi: 10.1093/clinids/23.5.1165.
9
Nocardiosis.诺卡菌病
Clin Infect Dis. 1996 Jun;22(6):891-903; quiz 904-5. doi: 10.1093/clinids/22.6.891.
10
Nocardia species: host-parasite relationships.诺卡氏菌属：宿主与寄生虫的关系。
Clin Microbiol Rev. 1994 Apr;7(2):213-64. doi: 10.1128/CMR.7.2.213.