Iwai Kunimitsu, Morimoto Shigeto, Matsumoto Masayuki
Department of Geriatric Medicine, Kanazawa Medical University.
Nihon Rinsho. 2005 Jun;63(6):1033-9.
Many clinical trials have been conducted to prevent cardiovascular complications and reduce mortality in hypertensive patients. Undoubted, but limited effects of beta-blocker and diuretic antihypertensive drugs had been established. Although angiotensin-converting enzyme inhibitor and angiotensin II receptor antagonist lowered the incidence of events and mortality less than classical antihypertensive drugs, recent studies revealed that prompt and enough lowering the blood pressure is more important than choosing the types of drugs.
已经进行了许多临床试验以预防心血管并发症并降低高血压患者的死亡率。毫无疑问，β受体阻滞剂和利尿降压药的效果有限。尽管血管紧张素转换酶抑制剂和血管紧张素II受体拮抗剂降低事件发生率和死亡率的效果不如经典降压药，但最近的研究表明，迅速且充分地降低血压比选择药物类型更重要。
