Saito Fumio, Takahashi Atsuhiko, Kushiro Toshio
Department of Cardiology, Surugadai Nihon University Hospital.
Nihon Rinsho. 2005 Jun;63(6):1078-85.
Considerable evidence of the usefulness of antihypertensive therapy in elderly hypertensive patients has been shown by the clinical intervention studies in western countries, using diuretics, beta-blockers, Ca antagonist, angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. Only two intervention studies on elderly hypertensive patients, which are NICS-EH and JATE, have been reported in Japan. Several Japanese intervention studies, such as JATOS, COPE, CASE-J, HOMED-BP and VALISH which conducted recently will provide us with new evidence in elderly hypertensive patients. We summarize the content of intervention studies on elderly hypertensive patients in western countries and Japan.
西方国家的临床干预研究已表明，使用利尿剂、β受体阻滞剂、钙拮抗剂、血管紧张素转换酶抑制剂和血管紧张素II受体阻滞剂进行降压治疗对老年高血压患者是有用的，且有大量证据支持。在日本，仅报道了两项针对老年高血压患者的干预研究，即NICS-EH和JATE。日本最近开展的几项干预研究，如JATOS、COPE、CASE-J、HOMED-BP和VALISH，将为我们提供关于老年高血压患者的新证据。我们总结了西方国家和日本针对老年高血压患者的干预研究内容。
