Colitz Carmen M H
Dept. of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon Tharp St., 335 VMAB, Columbus, OH 43210, USA.
Clin Tech Small Anim Pract. 2005 May;20(2):117-20. doi: 10.1053/j.ctsap.2004.12.016.
Uveitis is the inflammation of any or all parts of the vascular tunic of the eye; the vascular tunic includes the iris, the ciliary body, and choroid. A good knowledge base, up-to-date reference materials, and good instruments will improve the diagnosis of uveitis. Feline uveitis can be caused by numerous infectious agents in addition to neoplasia and less likely trauma. The infectious causes most commonly associated with feline uveitis include feline leukemia virus, feline immunodeficiency virus, feline infectious peritonitis, systemic fungal infections, toxoplasmosis, and bartonellosis. Neoplastic causes of uveitis can be primary or secondary. Iris melanoma is the most common primary uveal neoplasia and trauma-associated sarcoma is the second most common primary uveal neoplasia. Treatment for the clinical signs of anterior uveitis include topical steroidal or non-steroidal anti-inflammatory agents, parasympatholytic agents for ciliary spasm, to keep the pupil dilated, and to prevent posterior synechia. Posterior uveitis should be treated with systemic medications that will address the underlying cause. Enucleation of blind, painful eyes not responsive to medications is a means to alleviate the animal's discomfort and to further diagnose the underlying cause.
葡萄膜炎是指眼血管膜任何部分或全部的炎症;血管膜包括虹膜、睫状体和脉络膜。丰富的知识库、最新的参考资料以及精良的仪器将有助于提高葡萄膜炎的诊断水平。除肿瘤形成以及较少见的外伤外,猫葡萄膜炎可由多种感染因子引起。与猫葡萄膜炎最常相关的感染病因包括猫白血病病毒、猫免疫缺陷病毒、猫传染性腹膜炎、全身性真菌感染、弓形虫病和巴尔通体病。葡萄膜炎的肿瘤病因可为原发性或继发性。虹膜黑色素瘤是最常见的原发性葡萄膜肿瘤,外伤相关肉瘤是第二常见的原发性葡萄膜肿瘤。前葡萄膜炎临床症状的治疗包括局部使用甾体或非甾体抗炎药、用于睫状肌痉挛的抗副交感神经药,以保持瞳孔散大并防止后粘连。后葡萄膜炎应使用针对潜在病因的全身性药物进行治疗。对药物无反应的盲眼、疼痛眼进行眼球摘除是减轻动物不适并进一步诊断潜在病因的一种方法。