Perdonà Sisto, Autorino Riccardo, Gallo Luigi, DE Sio Marco, Marra Luigi, Claudio Luigi, Caracò Corrado, Franco Renato, Fazzioli Flavio, Gallo Antonio
Department of Urology, National Cancer Institute, I.R.C.C.S. Fondazione 'G.Pascale', Naples, Italy.
Int J Urol. 2005 Apr;12(4):401-4. doi: 10.1111/j.1442-2042.2005.01060.x.
Solitary metastases to the small bones and/or to the soft tissue of the hands and feet (acrometastases) are rare. We report a case of renal cell carcinoma (RCC) with big toe metastasis revealed before the primary tumor became apparent. The best treatment for a single metastasis is always surgical excision, regardless of the lesion being synchronous or metachronous. The biological behavior of metastatic RCC is unpredictable and only early diagnosis and treatment may favorably affect patient survival. Thus, metastatic RCC should be included in the differential diagnosis of all enlarging cutaneous nodules, wherever they develop.
孤立性转移至小骨骼和/或手足软组织（肢端转移）较为罕见。我们报告一例肾细胞癌（RCC），其在原发肿瘤出现之前就已发现有大脚趾转移。对于单个转移灶，无论病变是同时性还是异时性，最佳治疗方法始终是手术切除。转移性RCC的生物学行为不可预测，只有早期诊断和治疗才可能对患者生存产生有利影响。因此，转移性RCC应纳入所有增大的皮肤结节的鉴别诊断中，无论其发生在何处。
