Ridgway Dan M, White Steven A, Kimber Rachel M, Nicholson Michael L
Division of Transplantation, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester, UK.
Transpl Int. 2005 Jul;18(7):828-34. doi: 10.1111/j.1432-2277.2005.00144.x.
Recent refinements in technique mean islet cell transplantation offers the chance of a cure to an increasing patient cohort with diabetes. Such developments put pressure upon the scarce resource of donor organs, with potential competition between the modalities of cellular and solid organ transplantation. This questionnaire based study examines current patterns of donor pancreas procurement and use. Reasons for non procurement are studied together with the attitudes of transplant professionals to pancreas allocation. The minority of potentially useful pancreata are currently made available to either whole pancreas or islet transplant programs. Whilst professionals appreciate the role of each modality, there is a need to define criteria for pancreas allocation to avoid under use of donor organs.
近期技术的改进意味着胰岛细胞移植为越来越多的糖尿病患者提供了治愈的机会。这些进展给稀缺的供体器官资源带来了压力，细胞移植和实体器官移植方式之间存在潜在竞争。这项基于问卷调查的研究考察了目前供体胰腺获取和使用的模式。研究了未进行获取的原因以及移植专业人员对胰腺分配的态度。目前，仅有少数潜在可用的胰腺提供给全胰腺或胰岛移植项目。虽然专业人员认识到每种移植方式的作用，但仍需要确定胰腺分配标准，以避免供体器官利用不足。
