McMillan A, Manavi K, Young H
Department of Genitourinary Medicine, Edinburgh Royal Infirmary, Lothian University Hospitals NHS Trust, Lauriston Building, 39 Lauriston Place, Edinburgh EH3 9HA, UK.
Int J STD AIDS. 2005 May;16(5):357-61. doi: 10.1258/0956462053888925.
The aim of this retrospective study was to determine the prevalence of Chlamydia trachomatis co-infection in men with gonorrhoea attending a sexually transmitted diseases clinic in Edinburgh, Scotland. During the study period, there were 660 cases of culture-proven gonorrhoea. Chlamydial DNA was detected in the urethra in 79 (31%; 95% confidence interval [CI], 25-37%) heterosexual men who have sex with women (MSW); the median age was significantly lower than those with gonorrhoea alone (24.0 versus 30.0; P <0.0005). The prevalence of urethral chlamydial infection among MSW was significantly higher than among men who have sex with men (MSM) (32 [12%; 95% CI, 8-16%] of 268 MSM) (chi2 = 27.21; P <0.001). Sixteen (24%; 95% CI, 14-34%) of 68 MSM with rectal gonorrhoea had concurrent rectal chlamydial infection. The high prevalence of concurrent gonorrhoea and chlamydiae therefore warrants empirical treatment and/or testing for chlamydia in all men with urethral gonorrhoea.
这项回顾性研究的目的是确定在苏格兰爱丁堡一家性传播疾病诊所就诊的淋病男性患者中沙眼衣原体合并感染的患病率。在研究期间，共有660例经培养证实的淋病病例。在79名与女性发生性行为的异性恋男性（MSW）的尿道中检测到衣原体DNA（31%；95%置信区间[CI]，25 - 37%）；其年龄中位数显著低于单纯患淋病的男性（24.0对30.0；P <0.0005）。MSW中尿道衣原体感染的患病率显著高于与男性发生性行为的男性（MSM）（268名MSM中有32名[12%；95%CI，8 - 16%]）（χ2 = 27.21；P <0.001）。68名患有直肠淋病的MSM中有16名（2
4%；95%CI，14 - 34%）同时患有直肠衣原体感染。因此，淋病和衣原体合并感染的高患病率使得对所有患有尿道淋病的男性进行衣原体的经验性治疗和/或检测成为必要。
