Els M, Gross T, Ackermann C, Tondelli P
Chirurgische Klinik, St. Claraspital, Basel.
Schweiz Med Wochenschr. 1992 May 9;122(19):745-7.
Between 1984 and 1989 240 patients underwent radical abdominal resection of a rectal carcinoma. Out of 201 patients surviving 12 months or more postoperatively, 2 groups are surveyed. The first group presents patients undergoing adjunctive radiation therapy (n = 47), while the second group did not undergo postoperative radiation therapy (n = 134). Mean follow-up time postoperatively is 39 months. Within the irradiation group, the incidence of ileus was found to be 23% (11/47), and in the non-irradiated group 8% (11/134). Subsequent reoperations to clear intestinal obstruction were performed in 4% (5/134) of non-irradiated patients and 21% (10/47) of the irradiated group. Considering the increased risk of postoperative ileus after rectal resection for rectal carcinoma, the appropriateness of adjunctive radiation therapy should be carefully assessed.
1984年至1989年间,240例患者接受了直肠癌根治性腹部切除术。在术后存活12个月或更长时间的201例患者中,对两组进行了调查。第一组为接受辅助放疗的患者(n = 47),而第二组未接受术后放疗(n = 134)。术后平均随访时间为39个月。在放疗组中,肠梗阻的发生率为23%(11/47),在未放疗组中为8%(11/134)。未放疗患者中有4%(5/134)以及放疗组中有21%(10/47)随后进行了清除肠梗阻的再次手术。考虑到直肠癌直肠切除术后术后肠梗阻风险增加,应仔细评估辅助放疗的适宜性。