Schwarzenbach Othmar, Berlemann Ulrich, Stoll Thomas M, Dubois Gilles
dasRückenzentrum Thun, Bahnhofstrasse 3, 3600 Thun, Switzerland.
Orthop Clin North Am. 2005 Jul;36(3):363-72. doi: 10.1016/j.ocl.2005.03.001.
Posterior dynamic stabilization systems have to neutralize injurious forces and restore painless function of the spine segments and protect the adjacent segments. Because degenerative disc disease has many clinical manifestations, pedicular screw systems and interspinous implants have their indications. A dynamic stabilization device has to provide stability throughout its lifetime, unless it activates or allows reparative processes with a reversal of the degenerative changes. Anchorage to the bone is crucial, at least for pedicular systems. This is a great demand on spinal implants and assumes rest and motion going together. Our experience with DYNESYS has shown that this method has limitations in elderly patients with osteoporotic bone or in patients with a severe segmental macro-instability combined with degenerative olisthesis and advanced disc degeneration. Such cases have an increased risk of failure. Only future randomized evaluations will be able to address the potential reduction of accelerated adjacent segment degeneration. The few posterior dynamic stabilization systems that have had clinical applications so far have produced clinical outcomes comparable with fusion. No severe adverse events caused by these implants have been reported. Long-term follow-up data and controlled prospective randomized studies are not available for most of the cited implants but are essential to prove the safety, efficacy, appropriateness, and economic viability of these methods.
后路动态稳定系统必须抵消有害力量,恢复脊柱节段的无痛功能,并保护相邻节段。由于椎间盘退变疾病有多种临床表现,椎弓根螺钉系统和棘突间植入物都有各自的适应证。动态稳定装置必须在其整个使用寿命期间提供稳定性,除非它能激活或允许修复过程,使退变改变逆转。与骨骼的锚固至关重要,至少对于椎弓根系统来说是这样。这对脊柱植入物提出了很高的要求,并且意味着休息和运动要协同进行。我们使用DYNESYS的经验表明,这种方法在患有骨质疏松性骨的老年患者或患有严重节段性宏观不稳定合并退行性椎体滑脱和严重椎间盘退变的患者中存在局限性。此类病例失败风险增加。只有未来的随机评估才能解决加速相邻节段退变潜在减少的问题。迄今为止,少数已应用于临床的后路动态稳定系统产生了与融合相当的临床结果。尚未报告这些植入物引起的严重不良事件。对于大多数所引用的植入物,尚无长期随访数据和对照前瞻性随机研究,但这些对于证明这些方法的安全性、有效性、适用性和经济可行性至关重要。