Armato Samuel G
Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, MC 2026, Chicago, IL 60637, USA.
Lung Cancer. 2005 Jul;49 Suppl 1:S41-4. doi: 10.1016/j.lungcan.2005.03.011. Epub 2005 Apr 2.
Computed tomography (CT) has become an essential tool for monitoring the progression of mesothelioma tumor or a patient's response to treatment. Despite the accepted role of CT for the evaluation of mesothelioma, however, the current standard practice remains the manual measurement of tumor extent on CT scans. The process of manual measurement acquisition is tedious and subject to inconsistency. We have quantitatively assessed the variability of manual mesothelioma measurements both in baseline CT scans and in the context of tumor response classification across temporally sequential scans. To facilitate the acquisition of mesothelioma measurements, we have developed and evaluated computerized methods for the assessment of mesothelioma tumor thickness on CT scans; we anticipate that such computer-assisted approaches will make the radiologic assessment of mesothelioma more efficient, thus facilitating the establishment of improved clinical protocols.
计算机断层扫描（CT）已成为监测间皮瘤肿瘤进展或患者对治疗反应的重要工具。然而，尽管CT在间皮瘤评估中具有公认的作用，但目前的标准做法仍是在CT扫描上手动测量肿瘤范围。手动测量获取过程繁琐且存在不一致性。我们已经定量评估了在基线CT扫描以及跨时间序列扫描的肿瘤反应分类背景下，手动间皮瘤测量的变异性。为便于获取间皮瘤测量数据，我们开发并评估了用于在CT扫描上评估间皮瘤肿瘤厚度的计算机化方法；我们预计这种计算机辅助方法将使间皮瘤的放射学评估更高效，从而有助于建立改进的临床方案。
